Human HIF-1α Antibody Pair Set (E-KAB-0449)
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For research use only.
| Background |
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 ( HIF-1 ) , which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes , including those involved in energy metabolism , angiogenesis , apoptosis , and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization , tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
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| Synonyms |
HIF1A, HIF-1A, MOP1, PASD8, bHLHe78, basic helix-loop-helix transcription factor
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human HIF-1α in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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