Human IL-27 Antibody Pair Set (E-KAB-0225)
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For research use only.
| Background |
IL-27,a member of IL-12/IL-23 heterodimeric family of cytokines,has pleiotropic properties that can enhance or limit immune responses. IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types,including T cells,B cells,macrophages,dendritic cells,natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation,and enhances proliferation of naive CD4+T cells and naive B cells. It,however,also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.
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| Synonyms |
IL27, IL-27, IL-27A, IL27A, IL27p28, IL30, p28
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human IL-27 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This Antibody Pair Kit applies to the sandwich ELISA assay.
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