Human PECAM1/CD31 Antibody Pair Set (E-KAB-0531)
Add to cart
For research use only.
| Background |
Cell adhesion molecule which is required for leukocyte transendothelial migration ( TEM ) under most inflammatory conditions.Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment ( LBRC ) and is also essential for the LBRC membrane to be targeted around migrating leukocytes.Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions.Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils.Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal.Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells , PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes.
|
| Synonyms |
CD31, CD31/EndoCAM, Cluster of differentiation 31, EndoCAM, GPIIA', PECA1, PECAM-1, Platelet endothelial cell adhesion molecule
|
| Swissprot | |
| Reactivity |
Human
|
| Specificity |
Detects Human PECAM1/CD31 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.sample_type}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
No files available. Please enter the correct identification code in the search area to query the relevant documents.
| Title | Status | Valid until | Action | |
|---|---|---|---|---|
| {{v.文件名}} | {{v.status_str}} | {{v.timestamp_str}} | Download | / |
*Note：Please download the relevant files within the validity period. After expiration, file preview and download will not be available on the page.
Contact with Us
Toll-free: 1-888-852-8623
Tel: 1-832-243-6086
Add:
14780 Memorial Drive, Suite 105,
Houston, Texas, 77079, USA
Houston, Texas, 77079, USA
