Human SNCα Antibody Pair Set (E-KAB-0480)
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For research use only.
| Background |
Alpha-synuclein is a member of the synuclein family , which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
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| Synonyms |
SNC-A, aSYN, PD1, NACP, PARK1, PARK4,
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human SNCα in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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