ICA1 Polyclonal Antibody (E-AB-53153)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human brain |
| Dilution | IHC 1:50-1:100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ICA1 |
| Abbre | ICA1 |
| Synonyms | 69 kDa islet cell autoantigen, Diabetes mellitus type I autoantigen, ICA 1, ICA69, ICAp69, Ica1, Islet cell autoantigen 1, Islet cell autoantigen 1 (69kD), Islet cell autoantigen 1 69kDa, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69, OTTHUMP000 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytosol. Golgi apparatus membrane. Cytoplasmic vesicle>secretory vesicle membrane. Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Immunology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. |
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