IKK gamma Polyclonal Antibody

Uniprot : Q9Y6K9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14622

      Synonyms:IkB kinase associated protein 1, IkB kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma,AMCBX1,FIP 3,FIP-3,FIP3,Fip3p,I kappa B kinase gamma,I-kappa-B kinase subunit gamma,IkB kinase gamma subunit,IkB kinase subunit gamma,IkB kinase-associated protein 1,Ikbkg,IKK-gamma,IKKAP1,IKKG,IMD33,Incontinentia pigmenti,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase gamma,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase of,gamma,Inhibitor of nuclear factor kappa-B kinase subunit gamma,IP,IP1,IP2,IPD2,NEMO,NEMO,NF kappa B essential modifier,NF kappa B essential modulator,NF-kappa-B essential modifier,NF-kappa-B essential modulator,ZC2HC9

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms IkB kinase associated protein 1, IkB kinase subunit gamma, Inhibitor of nuclear factor kappa B kinase subunit gamma,AMCBX1,FIP 3,FIP-3,FIP3,Fip3p,I kappa B kinase gamma,I-kappa-B kinase subunit gamma,IkB kinase gamma subunit,IkB kinase subunit gamma,IkB kinase-associated protein 1,Ikbkg,IKK-gamma,IKKAP1,IKKG,IMD33,Incontinentia pigmenti,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase gamma,Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase of,gamma,Inhibitor of nuclear factor kappa-B kinase subunit gamma,IP,IP1,IP2,IPD2,NEMO,NEMO,NF kappa B essential modifier,NF kappa B essential modulator,NF-kappa-B essential modifier,NF-kappa-B essential modulator,ZC2HC9
      Swissprot Q9Y6K9
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human IKBKG
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
      Tissue specificity Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. 

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using IKK gamma Polyclonal Antibody at dilution 1:40

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