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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human IL18BP
Abbre IL18BP
Synonyms I18BP,  IL18 BP,  IL18 BPa,  IL-18BP,  IL18BPa,  Interleukin 18 binding protein,  Interleukin-18-binding protein,  MC51L 53L 54L homolog gene product,  Tadekinig alfa,  Tadekinig-alfa,  Tadekinig-alfa and IL18BP,  IL18BP
Swissprot
Cellular Localization Secreted.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Clones

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Unconjugated

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