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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution IHC 1:50-1:200
Isotype Rabbit IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human IL18R1
Abbre IL18R1
Synonyms alpha,  alpha chain,  CD218 antigen-like family member A,  CD218a,  CDw218a,  CDw218a antigen,  IL 1Rrp,  IL-18R,  IL-18R-1,  IL-18R1,  IL-1Rrp,  IL-1Rrp1,  IL1 receptor related protein,  IL1 receptor-related protein,  IL18R,  IL18R&,  IL18R1,  IL18RA,  Il18ralpha,  IL1R-rp,  IL1RRP,  Interleukin 18 receptor,  Interleukin 18 receptor 1,  Interleukin-18 receptor 1
Swissprot
Calculated MW 62.3 kDa
Cellular Localization Membrane
Tissue Specificity Highly expressed in leukocytes, spleen, lung. Also expressed, but at lower levels, in liver, small intestine, colon, prostate, thymus, placenta, and heart. Specifically coexpressed with IL18R1 in Th1 cells (PubMed:10653850, PubMed:10925275, PubMed:11046021).
Concentration 0.60 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Immunology
Conjugation Unconjugated
Storage Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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