IL33 Polyclonal Antibody (E-AB-17914)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colorectal cancer, Human thyroid cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IL33 |
| Abbre | IL33 |
| Synonyms | C9orf, C9orf26, CHROMOSOME 9 OPEN READING FRAME 26, DKFZp586H0523, DVS, DVS27, DVS27 related protein, IL 1F11, IL 33, IL-1F, IL-1F11, IL-33, IL1F, IL1F11, IL33, Interleukin, Interleukin 1 family member 11, Interleukin 33, INTERLEUKIN 33 NFHEV, Interleukin 33 precursor, Interleukin-1 family member 11, Interleukin-33, Interleukin-33 (109-270), Interleukin33, NF HEV, NF-HEV, NFEHEV, NFHEV, Nuclear factor for high endothelial venules, Nuclear factor from high endothelial venules, OTTHUMP00000021041, RP11 575C20.2 |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome. Cytoplasmic vesicle, secretory vesicle. Secreted. Associates with heterochromatin and mitotic chromosomes (PubMed:17185418). |
| Concentration | 0.66 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | IL-33 is an IL-1 family cytokine and nuclear alarmin,is constitutively expressed in epithelial barrier tissues and human blood vessels. IL-33 is involved in the maturation of Th2 cells and the activation of mast cells,basophils,eosinophils and natural killer cells. It also acts as a chemoattractant for Th2 cells,and may function as an "alarmin",that amplifies immune responses during tissue injury. |
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