KIF2C Polyclonal Antibody (E-AB-18750)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human KIF2C |
| Abbre | KIF2C |
| Synonyms | 4930402F02Rik, CT139, ESTM5, KIF 2C, KIF2C, Kinesein Family Member 2C, Kinesin family member 2C, Kinesin like 6, Kinesin like protein 6, Kinesin like protein KIF2C, Kinesin-like pr, Kinesin-like protein 6, kif2c, kinesin like 6 (mitotic centromere associated kinesin) |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Nucleus. Chromosome>centromere. Chromosome>centromere>kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2. |
| Concentration | 1.14 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. |
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