KIF3A Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Mouse brain,Human fetal brain,Human brain malignant glioma |
Dilution |
WB 1:200-1:1000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human KIF3A |
Abbre | KIF3A |
Synonyms | KIF 3;KIF 3A;KIF3;Kif3a;KIF3A;Kifl;Kinesin family member 3A;Kinesin family protein 3;Kinesin family protein 3A;Kinesin like protein KIF 3A;Kinesin like protein KIF3A;Kinesin-like protein KIF3A;Kns3;Microtubule plus end directed kinesin motor 3A;Microtubule plus end-directed kinesin motor 3A |
Swissprot | |
Calculated MW | 80kDa |
Cellular Localization | Cytoplasm>cytoskeleton. |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience; Signal Transduction; Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Kinesin-like protein KIF3Ais aproteinthat in humans is encoded by theKIF3Agene. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol