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For research use only.

Verified Samples Verified Samples in IF: A549
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human LECT1 (NP_008946.1).
Abbre LECT1
Synonyms BRICD3,  CHM-I,  CHM1,  CNMD,  LECT1,  MYETS1
Swissprot
Cellular Localization Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Unconjugated

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