LRIG1 Polyclonal Antibody (E-AB-12544)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human LRIG1 |
| Abbre | LRIG1 |
| Synonyms | Leucine rich repeat protein, Leucine rich repeat protein LRIG1, Leucine-rich repeats and immunoglobulin-like domains protein 1, leucine rich repeats and immunoglobulin like domains 1, leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene.It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family , MET and RET.Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. |
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