LTB Polyclonal Antibody

Uniprot : Q06643
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-13743

      Synonyms:LT beta,LT-beta,Ltb,lymphotoxin beta,Lymphotoxin-beta,p33,TNF-C,TNFC,TNFC,TNFSF3,Tumor necrosis factor C,Tumor necrosis factor ligand superfamily member 3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms LT beta,LT-beta,Ltb,lymphotoxin beta,Lymphotoxin-beta,p33,TNF-C,TNFC,TNFC,TNFSF3,Tumor necrosis factor C,Tumor necrosis factor ligand superfamily member 3
      Swissprot Q06643
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthetic peptide of human LTB
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:30-1:150
      Concentration 0.9 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Tissue specificity Spleen and thymus.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LTB Polyclonal Antibody at dilution 1:45

      Immunohistochemistry of paraffin-embedded Tonsil tissue using LTB Polyclonal Antibody at dilution of 1:90(Detected by lifespan)

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