MAD1L1 Polyclonal Antibody

Uniprot : Q9Y6D9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14200

      Synonyms:hMAD1,HsMAD1,MAD1,MAD1 mitotic arrest deficient like 1 (yeast),MAD1-like protein 1,MAD1L1,MD1L1,Mitotic arrest deficient 1,Mitotic arrest deficient 1-like protein 1,Mitotic checkpoint MAD1 protein homolog,Mitotic spindle assembly checkpoint protein MAD1,PIG9,Tax binding protein 181,Tax-binding protein 181,TP53I9,Tumor protein p53 inducible protein 9,TXBP181

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms hMAD1,HsMAD1,MAD1,MAD1 mitotic arrest deficient like 1 (yeast),MAD1-like protein 1,MAD1L1,MD1L1,Mitotic arrest deficient 1,Mitotic arrest deficient 1-like protein 1,Mitotic checkpoint MAD1 protein homolog,Mitotic spindle assembly checkpoint protein MAD1,PIG9,Tax binding protein 181,Tax-binding protein 181,TP53I9,Tumor protein p53 inducible protein 9,TXBP181
      Swissprot Q9Y6D9
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human MAD1L1
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:500-1:2000
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Chromosome>centromere>kinetochore. Cytoplasm>cytoskeleton>microtubule organizing center>centrosome. Cytoplasm>cytoskeleton>spindle. From the beginning to the end of mitosis, it is seen to move from a diffusely nuclear distribution to the centrosome, to the spindle midzone and finally to the midbody. Colocalizes with NEK2 at the kinetochore.
      Tissue specificity Expressed weakly at G0/G1 and highly at late S and G2/M phase.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts witHuman, MouseAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.

      Images

      Western Blot analysis of Hela, 231, hepG2 and Raji cell using MAD1L1 Polyclonal Antibody at dilution of 1:500

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