MARK1 Polyclonal Antibody

Uniprot : Q9P0L2
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14680

      Synonyms:KIAA1477,MAP/microtubule affinity regulating kinase 1,MAP/microtubule affinity-regulating kinase 1,MARK 1,MARK,Mark1,MARK1,MGC126512,MGC126513,Serine/threonine protein kinase MARK1,Serine/threonine-protein kinase MARK1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms KIAA1477,MAP/microtubule affinity regulating kinase 1,MAP/microtubule affinity-regulating kinase 1,MARK 1,MARK,Mark1,MARK1,MGC126512,MGC126513,Serine/threonine protein kinase MARK1,Serine/threonine-protein kinase MARK1
      Swissprot Q9P0L2
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human MARK1
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:500-1:2000
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm>cytoskeleton. Appears to localize to an intracellular network.
      Tissue specificity Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.

      Images

      Western Blot analysis of Mouse heart and brain tissue using MARK1 Polyclonal Antibody at dilution of 1:500

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