MLH1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human cervical cancer,Human thyroid cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human MLH1 |
Abbre | MLH1 |
Synonyms | COCA 2;COCA2;DNA mismatch repair protein Mlh1;FCC 2;FCC2;hMLH 1;hMLH1;HNPCC 2;HNPCC;HNPCC2;MGC5172;MLH 1;MLH1;MLH1;MutL homolog 1 (E. coli);MutL homolog 1;MutL homolog 1 colon cancer nonpolyposis type 2;MutL homolog 1;colon cancer;nonpolyposis type 2 (E. coli);MutL protein homolog 1;MutL;E. coli;homolog of;1 |
Swissprot | |
Cellular Localization | Nucleus |
Concentration | 0.8 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol