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MLH1 Polyclonal Antibody

Cat:E-AB-14226
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in IHC:Human cervical cancer,Human thyroid cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human MLH1
Abbre MLH1
Synonyms COCA 2;COCA2;DNA mismatch repair protein Mlh1;FCC 2;FCC2;hMLH 1;hMLH1;HNPCC 2;HNPCC;HNPCC2;MGC5172;MLH 1;MLH1;MLH1;MutL homolog 1 (E. coli);MutL homolog 1;MutL homolog 1 colon cancer nonpolyposis type 2;MutL homolog 1;colon cancer;nonpolyposis type 2 (E. coli);MutL protein homolog 1;MutL;E. coli;homolog of;1
Swissprot
Cellular Localization Nucleus
Concentration 0.8 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.