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Mouse IL-1β(Interleukin 1 Beta) ELISA Kit

Citations(117)Uniprot : P10749

Cat.No.:E-EL-M0037
Reactivity: Mouse

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96T
48T
24T
96T*5
96T*10

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Product Details

Properties

Assay type	Sandwich-ELISA
Format	96T/48T
Assay time	3.5h
Detection range	7.81-500 pg/mL
Sensitivity	4.69 pg/mL
Sample type &Sample volume	serum, plasma and other biological fluids; 100μL
Specificity	This kit recognizes Mouse IL-1β in samples. No significant cross-reactivity or interference between Mouse IL-1β and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of Mouse IL-1β concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse IL-1β. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse IL-1β and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse IL-1β, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Mouse IL-1β. You can calculate the concentration of Mouse IL-1β in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL	-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL
HRP Conjugate Diluent	1 vial, 14 mL
Concentrated Wash Buffer (25×)	1 vial, 30 mL
Substrate Reagent	1 vial, 10 mL	2-8℃(Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Mouse IL-1β were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Mouse IL-1β were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	26.40	59.30	201.20	27.30	57.80	199.40
Standard deviation	1.70	3.20	10.10	1.80	2.40	8.80
CV (%)	6.44	5.40	5.02	6.59	4.15	4.41

Recovery

The recovery of Mouse IL-1β spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	88-103	96
EDTA plasma (n=8)	91-104	97
Cell culture media (n=8)	91-107	98

Linearity

Samples were spiked with high concentrations of Mouse IL-1β and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database Links	SwissProt: P10749
Synonyms	IL1B, IL1-BETA, IL1F2, catabolin
Research Area	Cancer

Assay Procedures

	1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
	2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
	3. Aspirate and wash the plate for 3 times
	4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
	5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
	6. Add 50μL Stop Solution
	7. Read the plate at 450nm immediately. Calculation of the results

Citations

From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to orders@elabscience.com, we will get back to you with the reward after we confirm it ASAP!

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Molecular Cell (2017) IF: 14.714

Celastrol-Induced Nur77 Interaction With TRAF2 Alleviates Inflammation By Promoting Mitochondrial Ubiquitination And Autophagy.

DOI: 10.1016/j.molcel.2017.03.008
PMID: 28388439	Sample: Serum

Bone research (2018) IF: 9.3260

Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.

DOI: 10.1038/s41413-018-0012-0
PMID: 29619269

Free Radical Biology and Medicine (2020) IF: 6.17

Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study

DOI: 10.1016/j.freeradbiomed.2020.04.007
PMID: 32320747	Sample: Cell lysate,Cell culture supernatant

Free Radical Biology and Medicine (2019) IF: 6.17

Oral administration of 3,3'-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis

DOI: 10.1016/j.freeradbiomed.2019.09.009
PMID: 31521664	Sample: Bronchoalveolar Lavage Fluid,Tissue homogenate

Analytical chemistry (2018) IF: 6.042

A Redox-Responsive Self-Assembled Nanoprobe for Photoacoustic Inflammation Imaging to Assess Atherosclerotic Plaque Vulnerability

DOI: 10.1021/acs.analchem.8b04912
PMID: 30497260	Sample: Cell culture supernatant

Lipids (2020) IF: 5.219

Lipofundin Mediates the Major Inhibition of Intravenous Propofol in IL-1β Secretion and Phagocytosis of Staphylococcus aureus-Infected Macrophages

DOI: 10.1002/lipd.12207
PMID: 31838756	Sample: Cell culture medium

Frontiers in immunology (2019) IF: 5.085

Intranasal MMI-0100 Attenuates Aβ 1-42- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway

DOI: 10.3389/fimmu.2019.02707
PMID: 31849936	Sample: Tissue homogenate

Neurotherapeutics (2018) IF: 5.719

Spatial Training Ameliorates Long-Term Alzheimer's Disease-Like Pathological Deficits by Reducing NLRP3 Inflammasomes in PR5 Mice

DOI: 10.1007/s13311-018-00698-w
PMID: 30560481	Sample: Tissue homogenate

Oncotarget (2017) IF: 5.168

Wu-tou Decoction Attenuates Neuropathic Pain Via Suppressing Spinal Astrocytic IL-1R1/TRAF6/JNK Signaling.

DOI: 10.18632/oncotarget.21638
PMID: 29190962	Sample: Tissue homogenate

British Journal of Pharmacology (2017) IF: 5.491

The TIR/BB-Loop Mimetic AS-1 Prevents Non-Alcoholic Steatohepatitis And Hepatic Insulin Resistance By Inhibiting NLRP3-ASC Inflammasome Activation.

DOI: 10.1111/bph.13786
PMID: 28306139	Sample: Cell culture supernatant

Biochimica Et Biophysica Acta-Molecular Basis of Disease (2017) IF: 5.476

A Novel Mechanism Of Diabetic Vascular Endothelial Dysfunction: Hypoadiponectinemia-Induced NLRP3 Inflammasome Activation.

DOI: 10.1016/j.bbadis.2017.02.012
PMID: 28216285	Sample: Serum,Cell culture supernatant

Biochimica Et Biophysica Acta-Molecular Basis of Disease (2016) IF: 5.476

The TIR/BB-Loop Mimetic AS-1 Attenuates Mechanical Stress-Induced Cardiac Fibroblast Activation And Paracrine Secretion Via Modulation Of Large Tumor Suppressor Kinase 1.

DOI: 10.1016/j.bbadis.2016.03.002
PMID: 26964796	Sample: Cell culture supernatant

Food & Function (2020) IF: 4.171

Melatonin as an inducer of arecoline and their coordinated roles in anti-oxidative activity and immune responses

DOI: 10.1039/d0fo01841d
PMID: 32955540	Sample: Plasma

Food & Function (2020) IF: 4.171

Flaxseed oligosaccharides alleviate DSS-induced colitis through modulation of gut microbiota and repair of the intestinal barrier in mice

DOI: 10.1039/d0fo01105c
PMID: 32856645	Sample: Serum,Tissue homogenate

Aging (2020) IF: 4.831

Lipopolysaccharide upregulates miR-132/212 in Hirschsprung-associated enterocolitis, facilitating pyroptosis by activating NLRP3 inflammasome via targeting Sirtuin 1 (SIRT1)

DOI: 10.18632/aging.103852
PMID: 32950974	Sample: Serum

ACS Chemical Neuroscience (2020) IF: 4.486

MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis

DOI: 10.1021/acschemneuro.0c00268
PMID: 32786312	Sample: Serum

Neuropharmacology (2020) IF: 4.431

Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice

DOI: 10.1016/j.neuropharm.2020.108044
PMID: 32179291	Sample: Cell lysate

Ecotoxicology and Environmental Safety (2020) IF: 4.872

Silica particles disorganize the polarization of pulmonary macrophages in mice

DOI: 10.1016/j.ecoenv.2020.110364
PMID: 32114243	Sample: Tissue homogenate

Aging (2020) IF: 4.831

Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis

DOI: 10.18632/aging.103215
PMID: 32432571	Sample: Cell culture supernatant,Tissue homogenate

Frontiers in Cellular and Infection Microbiology (2020) IF: 4.123

Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways

DOI: 10.3389/fcimb.2020.00196
PMID: 32432055	Sample: Cell culture supernatant

Biomolecules (2020) IF: 4.082

Preparation, Characterization, and Immuno-Enhancing Activity of Polysaccharides from Glycyrrhiza uralensis

DOI: 10.3390/biom10010159
PMID: 31963790	Sample: Cell culture supernatant,Cell sample

Biomedicine & Pharmacotherapy (2019) IF: 4.545

Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways

DOI: 10.1016/j.biopha.2019.109166
PMID: 31255993	Sample: Cell culture supernatant

The Journal of nutrition (2019) IF: 4.281

Lactobacillus acidophilus Exerts Neuroprotective Effects in Mice with Traumatic Brain Injury

DOI: 10.1093/jn/nxz105
PMID: 31174208	Sample: Serum,Tissue homogenate

ACS chemical neuroscience (2019) IF: 4.486

Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death

DOI: 10.1021/acschemneuro.9b00539
PMID: 31682397	Sample: Tissue homogenate

Scientific reports (2018) IF: 4.122

Ageratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis

DOI: 10.1038/s41598-018-34492-7
PMID: 30375483	Sample: Serum,Tissue homogenate

Scientific Reports (2017) IF: 4.259

Glycyrrhiza Uralensis Water Extract Enhances Dendritic Cell Maturation And Antitumor Efficacy Of HPV Dendritic Cell-Based Vaccine.

DOI: 10.1038/srep43796
PMID: 28272545	Sample: Cell culture supernatant

Frontiers in Aging Neuroscience (2015) IF: 4.504

PGC-1α Silencing Compounds The Perturbation Of Mitochondrial Function Caused By Mutant SOD1 In Skeletal Muscle Of ALS Mouse Model.

DOI: 10.3389/fnagi.2015.00204
PMID: 26539112	Sample: Serum

Neurochemistry International (2020) IF: 3.881

Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-κB, p38 MAPK/JNK, Nrf2/ARE signaling

DOI: 10.1016/j.neuint.2020.104835
PMID: 32853749	Sample: Serum

Life Sciences (2020) IF: 3.647

Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways

DOI: 10.1016/j.lfs.2020.118546
PMID: 33035580	Sample: Serum

Life Sciences (2020) IF: 3.647

DHCR24 overexpression modulates microglia polarization and inflammatory response via Akt/GSK3β signaling in Aβ 25-35 treated BV-2 cells

DOI: 10.1016/j.lfs.2020.118470
PMID: 32950573	Sample: Cell sample

Life Sciences (2020) IF: 3.647

Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE

DOI: 10.1016/j.lfs.2020.118222
PMID: 32768577	Sample: Serum

Life Sciences (2020) IF: 3.647

Sevoflurane up-regulates microRNA-204 to ameliorate myocardial ischemia/reperfusion injury in mice by suppressing Cotl1

DOI: 10.1016/j.lfs.2020.118162
PMID: 32730836	Sample: Tissue homogenate

International Immunopharmacology (2020) IF: 3.943

miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway

DOI: 10.1016/j.intimp.2020.107016
PMID: 33039954	Sample: Serum

International Immunopharmacology (2020) IF: 3.943

Myricitrin pretreatment ameliorates mouse liver ischemia reperfusion injury

DOI: 10.1016/j.intimp.2020.107005
PMID: 33045574	Sample: Serum

International Immunopharmacology (2020) IF: 3.943

COX-2-PGE 2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice

DOI: 10.1016/j.intimp.2020.106801
PMID: 32702600	Sample: Tissue homogenate

European Review for Medical and Pharmacological Sciences (2020) IF: 3.024

miR-181-5p protects mice from sepsis via repressing HMGB1 in an experimental model

DOI: 10.26355/eurrev_202009_23063
PMID: 33015817	Sample: Serum

European review for medical and pharmacological sciences (2020) IF: 3.024

Effect of β-casomorphin-7 on myocardial hypertrophy in hyperthyroidism-induced cardiomyopathy

DOI: 10.26355/eurrev_202006_21536
PMID: 32572935	Sample: Serum,Tissue homogenate

European Journal of Pharmacology (2020) IF: 3.263

iTRAQ-based proteomics and in vitro experiments reveals essential roles of ACE and AP-N in the renin-angiotensin system-mediated congenital ureteropelvic junction obstruction

DOI: 10.1016/j.yexcr.2020.112086
PMID: 32416091	Sample: Serum,Cell sample

Brain Research Bulletin (2020) IF: 3.37

Biological evaluation of naturally occurring bulbocodin D as a potential multi-target agent for Alzheimer's disease

DOI: 10.1016/j.brainresbull.2020.09.017
PMID: 32991975	Sample: Cell culture supernatant

American Journal of Translational Research (2020) IF: 3.375

Overexpression of lncRNA Gm43050 alleviates apoptosis and inflammation response induced by sevoflurane treatment by regulating miR-640/ZFP91


PMID: 32913509	Sample: Cell culture supernatant

Journal of Drug Targeting (2020) IF: 3.38

Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer's disease in intracerebroventricular streptozotocin model for brain delivery

DOI: 10.1080/1061186X.2020.1817041
PMID: 32876502	Sample: Tissue homogenate

Experimental Biology and Medicine (2020) IF: 3.139

Exosomes derived from synovial fibroblasts under hypoxia aggravate rheumatoid arthritis by regulating Treg/Th17 balance

DOI: 10.1177/1535370220934736
PMID: 32615822	Sample: Cell culture medium

Neurochemical Research (2020) IF: 3.038

Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage

DOI: 10.1007/s11064-020-03012-3
PMID: 32170675	Sample: Tissue homogenate

International Immunopharmacology (2020) IF: 3.943

4-hydroxybenzo[d]oxazol-2(3H)-one ameliorates LPS/D-GalN-induced acute liver injury by inhibiting TLR4/NF-κB and MAPK signaling pathways in mice

DOI: 10.1016/j.intimp.2020.106445
PMID: 32272395	Sample: Tissue homogenate

Investigative Ophthalmology & Visual Science (2020) IF: 3.47

Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis

DOI: 10.1167/iovs.61.4.48
PMID: 32347916	Sample: Cell culture supernatant

IUBMB life (2020) IF: 3.244

Blockade of high mobility group box 1 involved in the protective of curcumin on myocardial injury in diabetes in vivo and in vitro

DOI: 10.1002/iub.2226
PMID: 31909882	Sample: Serum

International Immunopharmacology (2020) IF: 3.943

Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation

DOI: 10.1016/j.intimp.2019.106181
PMID: 31926446	Sample: Cell sample,Tissue homogenate

Scientific reports (2020) IF: 3.998

Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

DOI: 10.1038/s41598-020-66789-x
PMID: 32555320	Sample: Serum

Journal of Functional Foods (2020) IF: 3.701

Anti-fatigue activity of purified anthocyanins prepared from purple passion fruit (P. edulis Sim) epicarp in mice

DOI: 10.1016/j.jff.2019.103725
PMID: 99999999	Sample: Tissue homogenate

International Immunopharmacology (2020) IF: 3.943

Inhibition of LOX-1 prevents inflammation and photoreceptor cell death in retinal degeneration

DOI: 10.1016/j.intimp.2020.106190
PMID: 31945611	Sample: Cell culture supernatant

Journal of biochemical and molecular toxicology (2019) IF: 3.606

Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway

DOI: 10.1002/jbt.22389
PMID: 31468582	Sample: Tissue homogenate

International immunopharmacology (2019) IF: 3.943

Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation

DOI: 10.1016/j.intimp.2019.105915
PMID: 31639617	Sample: Serum,Cell culture supernatant

American Journal of Translational Research (2019) IF: 3.375

Xiaoyaosan prevents atherosclerotic vulnerable plaque formation through heat shock protein/glucocorticoid receptor axis-mediated mechanism


PMID: 31632527	Sample: Serum

Investigative ophthalmology & visual science (2018) IF: 3.27

Aspergillus fumigatus Increased PAR-2 Expression and Elevated Proinflammatory Cytokines Expression Through the Pathway of PAR-2/ERK1/2 in Cornea

DOI: 10.1167/iovs.17-21887
PMID: 29332129	Sample: Tissue homogenate

International immunopharmacology (2018) IF: 3.118

Interaction of mannose binding lectin and other pattern recognition receptors in human corneal epithelial cells during Aspergillus fumigatus infection

DOI: 10.1016/j.intimp.2018.08.003
PMID: 30096599	Sample: Tissue homogenate

Bioorganic chemistry (2019) IF: 3.929

Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer's disease

DOI: 10.1016/j.bioorg.2018.10.073
PMID: 30448726	Sample: Cell culture medium

American journal of translational research (2019) IF: 3.061

Vascular endothelial Cdc42 deficiency delays skin wound-healing processes by increasing IL-1β and TNF-α expression


PMID: 30787984	Sample: Tissue homogenate

Fish & shellfish immunology (2019) IF: 3.185

Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl) thio) isoquinoline in RAW264. 7 macrophages and a zebrafish model

DOI: 10.1016/j.fsi.2019.01.030
PMID: 30685466	Sample: Cell culture supernatant

Frontiers in endocrinology (2018) IF: 3.519

Verapamil ameliorates hepatic metaflammation by inhibiting thioredoxin-interacting protein/NLRP3 inflammasome activation

DOI: 10.3389/fendo.2018.00640
PMID: 30429827	Sample: Serum

Toxicology and applied pharmacology (2019) IF: 3.616

SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress

DOI: 10.1016/j.taap.2018.10.013
PMID: 30336174	Sample: Serum,Tissue homogenate

Journal of Functional Foods (2019) IF: 3.47

The protective effects of Chinese yam polysaccharide against obesity-induced insulin resistance

DOI: 10.1016/j.jff.2019.02.023
PMID: 99999999	Sample: Serum

International journal of molecular sciences (2019) IF: 3.687

Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways

DOI: 10.3390/ijms20051103
PMID: 30836660	Sample: Serum

Colloids and Surfaces B: Biointerfaces (2019) IF: 3.973

CD47-targeted bismuth selenide nanoparticles actualize improved photothermal therapy by increasing macrophage phagocytosis of cancer cells

DOI: 10.1016/j.colsurfb.2019.110546
PMID: 31606701	Sample: Plasma

Molecules (2019) IF: 3.06

Design, Synthesis and Investigation of the Potential Anti-inflammatory Activity of 7-O-Amide Hesperetin Derivatives

DOI: 10.3390/molecules24203663
PMID: 31614601	Sample: Cell culture supernatant

Biomedicine & Pharmacotherapy (2018) IF: 3.457

Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.

DOI: 10.1016/j.biopha.2018.07.081
PMID: 30119204	Sample: Serum

Front Pharmacol (2017) IF: 3.831

Quercetin Inhibits LPS-Induced Inflammation and ox-LDL-Induced Lipid Deposition.

DOI: 10.3389/fphar.2017.00040
PMID: 28217098	Sample: Cell

Biomedicine & Pharmacotherapy (2018) IF: 3.457

The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice.

DOI: 10.1016/j.biopha.2018.07.063
PMID: 30119194	Sample: Serum,Tissue homogenate

Neuroscience (2017) IF: 3.277

Blocking The CD38/cADPR Pathway Plays A Double-edged Role In LPS Stimulated Microglia.

DOI: 10.1016/j.neuroscience.2017.08.010
PMID: 28807785	Sample: Cell culture supernatant

Acta Pharmacologica Sinica (2017) IF: 3.223

Molecular Mechanisms Of the Analgesic Action Of Wu-tou Decoction On Neuropathic Pain In Mice Revealed Using Microarray And Network Analysis.

DOI: 10.1038/aps.2017.110
PMID: 28816231	Sample: Tissue homogenate

Acta Pharmacologica Sinica (2017) IF: 3.223

Osthole Prevents Acetaminophen-Induced Liver Injury In Mice.

DOI: 10.1038/aps.2017.129
PMID: 29022574	Sample: Tissue homogenate

International Journal of Chronic Obstructive Pulmonary Disease (2017) IF: 3.157

Repression Of Toll-Like Receptor-4 By microRNA-149-3p Is Associated With Smoking-Related COPD.

DOI: 10.2147/COPD.S128031
PMID: 28260877	Sample: Cell culture supernatant

Plants (2020) IF: 2.762

Phytochemical, Cytotoxicity, Antioxidant and Anti-Inflammatory Effects of Psilocybe Natalensis Magic Mushroom

DOI: 10.3390/plants9091127
PMID: 32878164	Sample: Cell culture supernatant

Journal of Neuroscience Methods (2020) IF: 2.214

Frequent exposure to varied home cage sizes alters pain sensitivity and some key inflammation-related biomarkers

DOI: 10.1016/j.jneumeth.2020.108890
PMID: 32768413	Sample: Tissue homogenate

Bioscience Reports (2020) IF: 2.942

Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation

DOI: 10.1042/BSR20192800
PMID: 32490526	Sample: Cell culture supernatant

Microbial Pathogenesis (2020) IF: 2.914

Exposure time determines the protective effect of Trichinella spiralis on experimental colitis

DOI: 10.1016/j.micpath.2020.104263
PMID: 32442663	Sample: Serum

Cytokine (2020) IF: 2.952

6-Gingerol attenuates macrophages pyroptosis via the inhibition of MAPK signaling pathways and predicts a good prognosis in sepsis

DOI: 10.1016/j.cyto.2019.154854
PMID: 31539844	Sample: Cell culture supernatant

Molecular Medicine Reports (2020) IF: 2.1

Coenzyme Q10 alleviates sevoflurane-induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

DOI: 10.3892/mmr.2020.11131
PMID: 32377738	Sample: Tissue homogenate

Experimental Physiology (2020) IF: 2.431

Knockout of MD1 contributes to sympathetic hyperactivity and exacerbates ventricular arrhythmias following heart failure with preserved ejection fraction via NLRP3 inflammasome activation

DOI: 10.1113/EP088390
PMID: 32240565	Sample: Tissue homogenate

PeerJ (2020) IF: 2.379

The immunostimulatory activity of polysaccharides from Glycyrrhiza uralensis

DOI: 10.7717/peerj.8294
PMID: 32030319	Sample: Tissue homogenate

Molecular medicine reports (2018) IF: 2.1

Dioscin prevents LPS-induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70

DOI: 10.3892/mmr.2018.8667
PMID: 29512786	Sample: Serum,Tissue homogenate

Inflammation (2018) IF: 2.884

miR-590-3p Attenuates Acute Kidney Injury by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 in Septic Mice

DOI: 10.1007/s10753-018-0921-5
PMID: 30392071	Sample: Serum

Molecular diversity (2019) IF: 2.229

Hybrids of oxoisoaporphine-tetrahydroisoquinoline: novel multi target inhibitors of infammation and amyloid-β aggregation in Alzheimer's disease

DOI: 10.1007/s11030-018-9905-5
PMID: 30603938	Sample: Cell culture medium

Journal of the Science of Food and Agriculture (2019) IF: 2.379

Effect and mechanism of citral against methicillin-resistant Staphylococcus aureus in vivo

DOI: 10.1002/jsfa.9677
PMID: 30891759	Sample: Serum

Journal of cellular biochemistry (2019) IF: 2.959

Attractylone Attenuates Sepsis-Associated Encephalopathy and Cognitive Dysfunction by Inhibiting Microglial Activation and Neuroinflammation

DOI: 10.1002/jcb.27983
PMID: 30672013	Sample: Cell culture supernatant,Tissue homogenate

Inflammation (2019) IF: 2.884

Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

DOI: 10.1007/s10753-019-00986-3
PMID: 30847744	Sample: Serum,Cell culture supernatant

Molecular and Cellular Biochemistry (2018) IF: 2.561

Propofol specifically suppresses IL-1β secretion but increases bacterial survival in Staphylococcus aureus-infected RAW264. 7 cells.

DOI: 10.1007/s11010-018-3348-2
PMID: 29667111	Sample: cell

Metabolic Brain Disease IF: 2.441

Gentiopicroside abrogates lipopolysaccharide-induced depressive-like behavior in mice through tryptophan-degrading pathway.

DOI: 10.1007/s11011-018-0246-y
PMID: 29948656	Sample: Plasma

European Journal of Pharmacology (2016) IF: 2.896

Liraglutide Attenuates Lipopolysaccharide-Induced Acute Lung Injury In Mice.

DOI: 10.1016/j.ejphar.2016.10.016
PMID: 27756605	Sample: Bronchoalveolar Lavage Fluid

Molecules (2017) IF: 2.861

Capparis Spinosa Fruit Ethanol Extracts Exert Different Effects On The Maturation Of Dendritic Cells.

DOI: 10.3390/molecules22010097
PMID: 28067853	Sample: Cell culture supernatant

Placenta (2015) IF: 2.759

The Effect Of Maternal Obesity On The Expression And Functionality Of Placental P-Glycoprotein: Implications In The Individualized Transplacental Digoxin Treatment For Fetal Heart Failure.

DOI: 10.1016/j.placenta.2015.08.007
PMID: 26311557	Sample: Plasma

Biochemical & Biophysical Research Communications (2015) IF: 2.466

Ghrelin Ameliorates Intestinal Barrier Dysfunction In Experimental Colitis By Inhibiting The Activation Of Nuclear Factor-Kappa B.

DOI: 10.1016/j.bbrc.2015.01.083
PMID: 25634696	Sample: Tissue homogenate

Food Science & Nutrition (2020) IF: 1.797

Subcutaneous administration of casein attenuates atherosclerotic progression in male apoE -/- mice fed with high-fat diet

DOI: 10.1002/fsn3.1638
PMID: 32724618	Sample: Plasma

Experimental and Therapeutic Medicine (2020) IF: 1.785

Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate-induced colitis

DOI: 10.3892/etm.2020.9138
PMID: 32934675	Sample: Serum

Bioscience, Biotechnology, and Biochemistry (2020) IF: 1.516

LncRNA TUG1 reverses LPS-induced cell apoptosis and inflammation of macrophage via targeting miR-221-3p/SPRED2 axis

DOI: 10.1080/09168451.2020.1806704
PMID: 32841583	Sample: Tissue homogenate

International journal of ophthalmology (2019) IF: 1.33

Expression and role of calcitonin gene-related peptide in mouse Aspergillus fumigatus keratitis

DOI: 10.18240/ijo.2019.05.01
PMID: 31131225	Sample: Cell culture supernatant

Canadian journal of physiology and pharmacology (2019) IF: 1.946

Role of Brd4 in the production of inflammatory cytokines in mouse macrophages treated with titanium particles

DOI: 10.1139/cjpp-2019-0142
PMID: 31330113	Sample: Cell culture supernatant

Neuroreport (2018) IF: 1.394

Gentiopicroside protects neurons from astrocyte-mediated inflammatory injuries by inhibition of nuclear factor-κB and mitogen-activated protein kinase signaling pathways

DOI: 10.1097/WNR.0000000000001082
PMID: 29958245	Sample: Cell culture supernatant

Experimental and therapeutic medicine (2018) IF: 1.41

miR-148a inhibits pro-inflammatory cytokines released by intervertebral disc cells by regulating the p38/MAPK pathway

DOI: 10.3892/etm.2018.6516
PMID: 30186499	Sample: Cell culture supernatant

Cellular & molecular biology letters (2019) IF: 1.291

Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling

DOI: 10.1186/s11658-018-0125-x
PMID: 30820195	Sample: Cell culture supernatant

Journal of biochemical and molecular toxicology (2019) IF: 1.837

Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats

DOI: 10.1002/jbt.22302
PMID: 30790395	Sample: Serum,Tissue homogenate

Cellular & molecular biology letters (2019) IF: 1.291

Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

DOI: 10.1186/s11658-019-0142-4
PMID: 30833971	Sample: Serum

BMC Pharmacology and Toxicology (2020) IF: 1.771

Impact of Lesinurad and allopurinol on experimental Hyperuricemia in mice: biochemical, molecular and Immunohistochemical study

DOI: 10.1186/s40360-020-0386-7
PMID: 32041665	Sample: Serum

Oncology Letters (2018) IF: 1.39

The Association Between Inflammation, The Microbiome and Urethane-induced Pulmonary Adenocarcinoma.

DOI: 10.3892/ol.2018.8167
PMID: 29725395

Molecular Medicine Reports (2018) IF: 1.692

Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses.

DOI: 10.3892/mmr.2018.8767
PMID: 29568928

Experimental and Therapeutic Medicine (2017) IF: 1.261

Effects Of Sepsis On The Metabolism Of Sphingomyelin And Cholesterol In Mice With Liver Dysfunction.

DOI: 10.3892/etm.2017.5226
PMID: 29285103	Sample: Plasma

Journal of Oleo Science (2015) IF: 1.076

A Comparative Study Of The Effects Upon LPS Induced Macrophage RAW264.7 Inflammation In Vitro Of The Lipids Of Hippocampus Trimaculatus Leach.

DOI: 10.5650/jos.ess15190
PMID: 26582156	Sample: Cell culture supernatant

Medical Science Monitor: International Medical Journal of Experimental and Clinical Research (2020)

Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis

DOI: 10.1016/j.toxlet.2020.07.028
PMID: 32768653	Sample: Cell culture supernatant,Tissue homogenate

Advances in Pharmacological and Pharmaceutical Sciences (2020)

Antihypernociceptive, Anxiolytic, and Antidepressant Properties of Aqueous and Ethanol Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Mice

DOI: 10.1155/2020/8886894
PMID: 33015629	Sample: Serum,Tissue homogenate

The FASEB Journal (2020)

CaMK4-dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis

DOI: 10.1096/fj.201902910RRR
PMID: 32862457	Sample: Cell culture supernatant,Tissue homogenate

Plant Archives (2020)

IMPACT OF BACTERIAL LIPOPOLYSACCHARIDE ON CYTOKINES RESPONSES AT PREGNANCY


PMID: 99999999	Sample: Serum

SSRN (2020)

Salidroside Attenuates Liver Injury in Diabetes Mice

DOI: 10.2139/ssrn.3546025
PMID: 99999999	Sample: Serum,Cell culture supernatant,Tissue homogenate

Journal of Cellular and Molecular Medicine (2020)

Polysaccharides from Dicliptera chinensis ameliorate liver disturbance by regulating TLR-4/NF-κB and AMPK/Nrf2 signalling pathways

DOI: 10.1111/jcmm.15286
PMID: 32337831	Sample: Serum,Tissue homogenate

Open access Macedonian journal of medical sciences (2019)

Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice

DOI: 10.3889/oamjms.2019.247
PMID: 31049081	Sample: Tissue homogenate

Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease (2019)

Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKC未-IRAK axis in adipocytes

DOI: 10.1016/j.bbadis.2018.10.036
PMID: 30391544	Sample: Cell culture supernatant

Naunyn-Schmiedeberg's archives of pharmacology (2019)

Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy in mice.

DOI: 10.1007/s00210-019-01626-1
PMID: 30759263	Sample: Serum,Spinal cord

BMC Complementary Medicine and Therapies (2020)

Shen-ling-bai-zhu-san ameliorates inflammation and lung injury by increasing the gut microbiota in the murine model of Streptococcus pneumonia-induced pneumonia

DOI: 10.1186/s12906-020-02958-9
PMID: 32460745	Sample: Tissue homogenate

Preprints (2019)

Ameliorative Effects of Lesinurad (Zurampic) on Experimental Hyperuricemia, Biochemical, Molecular and Immunohistochemical Study

DOI: 10.21203/rs.2.17096/v1
PMID: 99999999	Sample: Serum

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