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Mouse IL-6(Interleukin 6) ELISA Kit

  • Cat.No.:E-EL-M0044

  • Reactivity: Mouse

To Purchase E-EL-M0044

  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $495

Product Details


Assay type Sandwich-ELISA
Format 96T/48T
Assay time 3.5h
Detection range 31.25-2000 pg/mL
Sensitivity 18.75 pg/mL
Sample type &Sample volume serum, plasma and other biological fluids; 100μL
Specificity This kit recognizes Mouse IL-6 in samples. No significant cross-reactivity or interference between Mouse IL-6 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Mouse IL-6 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse IL-6. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse IL-6 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse IL-6, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Mouse IL-6. You can calculate the concentration of Mouse IL-6 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips
-20℃, 6 months
Reference Standard 96T: 2 vials
48T: 1 vial
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Substrate Reagent 1 vial, 10 mL 2-8℃(Protect from light)
Stop Solution 1 vial, 10 mL 2-8°C
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Technical Data


Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Mouse IL-6 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Mouse IL-6 were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 99.40 174.50 952.80 105.30 162.70 1040.70
Standard deviation 6.40 7.70 50.50 6.50 8.10 38.50
CV (%) 6.44 4.41 5.30 6.17 4.98 3.70


The recovery of Mouse IL-6 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-100 93
EDTA plasma (n=8) 88-101 94
Cell culture media (n=8) 89-104 95


Samples were spiked with high concentrations of Mouse IL-6 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt:   P08505
SynonymsIL6, BSF2, HGF, HSF, IFNB2, CDF
Research AreaCancer, Metabolism, Immunology, Neuroscience

Assay Procedures

elisa assay procedure 1

1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C

elisa assay procedure 2

2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C

elisa assay procedure 3

3. Aspirate and wash the plate for 3 times

elisa assay procedure 4

4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times

elisa assay procedure 5

5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C

elisa assay procedure 6

6. Add 50μL Stop Solution

elisa assay procedure 7

7. Read the plate at 450nm immediately. Calculation of the results


From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to, we will get back to you with the reward after we confirm it ASAP!

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  1. Advanced functional materials (2020) IF: 16.836
    Quantitative Photoacoustic Diagnosis and Precise Treatment of Inflammation In Vivo Using Activatable Theranostic Nanoprobe

    DOI: 10.1002/adfm.202001771

    Sample: Serum
  2. Sci Transl Med (2020) IF: 16.304
    Nuclear Receptor PXR Targets AKR1B7 to Protect Mitochondrial Metabolism and Renal Function in AKI

    DOI: 10.1126/scitranslmed.aay7591

    PMID: 32404507

    Sample: Serum
  3. Advanced Functional Materials (2019) IF: 16.836
    NIR/ROS-Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy

    DOI: 10.1002/adfm.201905758

    Sample: Serum
  4. Molecular Cell (2017) IF: 14.714
    Celastrol-Induced Nur77 Interaction With TRAF2 Alleviates Inflammation By Promoting Mitochondrial Ubiquitination And Autophagy.

    DOI: 10.1016/j.molcel.2017.03.008

    PMID: 28388439

    Sample: Serum
  5. NANO LETTERS (2019) IF: 11.238
    NanoRNP Overcomes Tumor Heterogeneity in Cancer Treatment

    DOI: 10.1021/acs.nanolett.9b02501

    PMID: 31593471

    Sample: Serum
  6. Biomaterials (2021) IF: 10.317
    Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease

    DOI: 10.1016/j.biomaterials.2021.120796

    PMID: 33894403

    Sample: Cell sample
  7. Journal Of Nanobiotechnology (2021) IF: 10.435
    Gold nanoparticles reduce inflammation in cerebral microvessels of mice with sepsis

    DOI: 10.1186/s12951-021-00796-6

    PMID: 33608025

    Sample: Tissue(brain)
  8. Journal of Controlled Release (2021) IF: 9.776
    Simultaneous blockage of contextual TGF-β by cyto-pharmaceuticals to suppress breast cancer metastasis

    DOI: 10.1016/j.jconrel.2021.06.012

    PMID: 34119557

    Sample: Serum
  9. Chem. Sci. (2020) IF: 9.346
    A tumor acidity activatable and Ca2+-assisted immuno-nanoagent enhances breast cancer therapy and suppresses cancer recurrence

    DOI: 10.1039/d0sc00293c

    Sample: Serum
  10. Bone research (2018) IF: 9.3260
    Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.

    DOI: 10.1038/s41413-018-0012-0

    PMID: 29619269

  11. Theranostics (2020) IF: 8.5790
    Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy

    DOI: 10.7150/thno.45028

    PMID: 32685027

    Sample: Serum
  12. British Journal of Pharmacology (2020) IF: 7.73
    Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters

    DOI: 10.1111/bph.14957

    PMID: 32000294

    Sample: Tissue homogenate
  13. Free Radical Biology and Medicine (2020) IF: 6.17
    Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study

    DOI: 10.1016/j.freeradbiomed.2020.04.007

    PMID: 32320747

    Sample: Cell lysate,Cell culture supernatant
  14. Free Radical Biology and Medicine (2019) IF: 6.17
    Oral administration of 3,3'-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis

    DOI: 10.1016/j.freeradbiomed.2019.09.009

    PMID: 31521664

    Sample: Bronchoalveolar Lavage Fluid,Tissue homogenate
  15. Acta Biomaterialia (2020) IF: 6.638
    Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer


    PMID: 32151700

    Sample: Whole Blood
  16. Analytical chemistry (2018) IF: 6.042
    A Redox-Responsive Self-Assembled Nanoprobe for Photoacoustic Inflammation Imaging to Assess Atherosclerotic Plaque Vulnerability

    DOI: 10.1021/acs.analchem.8b04912

    PMID: 30497260

    Sample: Cell culture supernatant
  17. Frontiers in Medicine (2021) IF: 5.08
    Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway

    DOI: 10.3389/fmed.2020.626140

    PMID: 33553218

    Sample: Tissue homogenate
  18. International Journal of Biological Macromolecules (2020) IF: 5.162
    A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways

    DOI: 10.1016/j.ijbiomac.2020.06.266

    PMID: 32621930

    Sample: Cell culture supernatant
  19. Oxidative Medicine and Cellular Longevity (2020) IF: 5.076
    The Inhibition of P-Selectin Reduced Severe Acute Lung Injury in Immunocompromised Mice

    DOI: 10.1155/2020/8430465

    PMID: 32377309

    Sample: Serum
  20. Oxidative Medicine and Cellular Longevity (2019) IF: 5.076
    Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2

    DOI: 10.1155/2019/4703253

    PMID: 31827675

    Sample: Serum
  21. Oxidative medicine and cellular longevity (2019) IF: 5.076
    Targeting IL-17A Improves the Dysmotility of the Small Intestine and Alleviates the Injury of the Interstitial Cells of Cajal during Sepsis

    DOI: 10.1155/2019/1475729

    PMID: 31531179

    Sample: Tissue homogenate
  22. Frontiers in immunology (2019) IF: 5.085
    Intranasal MMI-0100 Attenuates Aβ 1-42- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway

    DOI: 10.3389/fimmu.2019.02707

    PMID: 31849936

    Sample: Tissue homogenate
  23. Cellular Physiology and Biochemistry (2018) IF: 5.5
    The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice.

    DOI: 10.1159/000490185

    PMID: 29843136

    Sample: Serum
  24. Oncotarget (2017) IF: 5.168
    Regulatory role of NKG2D+ NK cells in intestinal lamina propria by secreting double-edged Th1 cytokines in ulcerative colitis.

    DOI: 10.18632/oncotarget.22132

    PMID: 29228739

    Sample: Tissue homogenate
  25. Oncotarget (2017) IF: 5.168
    Glioblastoma Progression Is Assisted By Induction Of Immunosuppressive Function Of Pericytes Through Interaction With Tumor Cells.

    DOI: 10.18632/oncotarget.19804

    PMID: 28978142

    Sample: Cell culture supernatant
  26. Molecules (2022) IF: 4.411
    The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues

    DOI: 10.3390/molecules27123682

    Sample: Tissue homogenate
  27. Molecules (2022) IF: 4.4
    Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway

    DOI: 10.3390/molecules27010078

    PMID: 35011304

    Sample: Serum
  28. Molecules (2021) IF: 4.41
    Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway

    DOI: 10.3390/molecules25163573

    PMID: 32781605

    Sample: Cell culture supernatant
  29. Food & Function (2020) IF: 4.171
    Flaxseed oligosaccharides alleviate DSS-induced colitis through modulation of gut microbiota and repair of the intestinal barrier in mice

    DOI: 10.1039/d0fo01105c

    PMID: 32856645

    Sample: Serum,Tissue homogenate
  30. Journal of Cellular and Molecular Medicine (2020) IF: 4.486
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    DOI: 10.1111/jcmm.15434

    PMID: 32519822

    Sample: Plasma
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    DOI: 10.1021/acs.jafc.0c01658

    Sample: Cell culture supernatant
  32. Neuropharmacology (2020) IF: 4.431
    Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice

    DOI: 10.1016/j.neuropharm.2020.108044

    PMID: 32179291

    Sample: Cell lysate
  33. Nutrients (2020) IF: 4.546
    Chinese Propolis Prevents Obesity and Metabolism Syndromes Induced by a High Fat Diet and Accompanied by an Altered Gut Microbiota Structure in Mice

    DOI: 10.3390/nu12040959

    PMID: 32235581

    Sample: Serum
  34. Biomedicine & Pharmacotherapy (2020) IF: 4.545
    MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway

    DOI: 10.1016/j.biopha.2020.110091

    PMID: 32278272

    Sample: Plasma
  35. Journal of agricultural and food chemistry (2020) IF: 4.192
    Novel Biomedical Functions of Surfactin A from Bacillus subtilis in Wound Healing Promotion and Scar Inhibition

    DOI: 10.1021/acs.jafc.0c01658

    PMID: 32412748

    Sample: Cell culture supernatant
  36. Journal of Agricultural and Food Chemistry (2020) IF: 4.192
    Modulation of Gut Microbiota by Fucoxanthin During Alleviation of Obesity in High-Fat Diet-Fed Mice

    DOI: 10.1021/acs.jafc.0c01467

    PMID: 32309947

    Sample: Serum,Tissue homogenate
  37. Microbial Cell Factories (2020) IF: 4.187
    A probiotic treatment increases the immune response induced by the nasal delivery of spore-adsorbed TTFC

    DOI: 10.1186/s12934-020-01308-1

    PMID: 32075660

    Sample: Cell culture supernatant
  38. Nutrients (2020) IF: 4.546
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    DOI: 10.3390/nu12010249

    PMID: 31963703

    Sample: Serum,Cell culture supernatant
  39. Food & Function (2020) IF: 4.171
    Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-κB pathways

    DOI: 10.1039/c9fo02202c

    PMID: 31859327

    Sample: Cell culture supernatant
  40. Nutrients (2020) IF: 4.546
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    DOI: 10.3390/nu12040901

    PMID: 32224881

    Sample: Tissue homogenate
  41. Biomedicine & Pharmacotherapy (2019) IF: 4.545
    Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways

    DOI: 10.1016/j.biopha.2019.109166

    PMID: 31255993

    Sample: Cell culture supernatant
  42. Ecotoxicology and Environmental Safety (2019) IF: 4.872
    Inflammatory kidney injury in trichloroethylene hypersensitivity syndrome mice: Possible role of C3a receptor in the accumulation of Th17 phenotype

    DOI: 10.1016/j.ecoenv.2019.109772

    PMID: 31614297

    Sample: Serum
  43. International journal of molecular sciences (2019) IF: 4.556
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    DOI: 10.3390/ijms20143605

    PMID: 31340581

    Sample: Serum,Cell culture supernatant
  44. ACS chemical neuroscience (2019) IF: 4.486
    Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death

    DOI: 10.1021/acschemneuro.9b00539

    PMID: 31682397

    Sample: Tissue homogenate
  45. Frontiers in microbiology (2018) IF: 4.019
    The influence of Acanthamoeba-Legionella interaction in the virulence of two different Legionella species.

    DOI: 10.3389/fmicb.2018.02962

    PMID: 30568639

    Sample: Cell culture supernatant
  46. Neurobiology of aging (2019) IF: 4.454
    CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

    DOI: 10.1016/j.neurobiolaging.2018.11.023

    PMID: 30594047

    Sample: Tissue homogenate,Cell culture medium
  47. Oxidative Medicine And Cellular Longevity (2016) IF: 4.593
    Hydrogen Sulfide Mitigates Kidney Injury In High Fat Diet-Induced Obese Mice.

    DOI: 10.1155/2016/2715718

    PMID: 27413418

    Sample: Plasma
  48. Scientific Reports (2017) IF: 4.259
    Glycyrrhiza Uralensis Water Extract Enhances Dendritic Cell Maturation And Antitumor Efficacy Of HPV Dendritic Cell-Based Vaccine.

    DOI: 10.1038/srep43796

    PMID: 28272545

    Sample: Cell culture supernatant
  49. Carbohydrate Polymers (2016) IF: 4.811
    Structural Analysis And Immunoregulation Activity Comparison Of Five Polysaccharides From Angelica Sinensis.

    DOI: 10.1016/j.carbpol.2015.12.050

    PMID: 26876821

    Sample: Cell culture supernatant
  50. International Journal of Nanomedicine (2016) IF: 4.3
    Effects Of Silver Nanoparticles In Combination With Antibiotics On The Resistant Bacteria Acinetobacter Baumannii.

    DOI: 10.2147/IJN.S104166

    PMID: 27574420

    Sample: Plasma
  51. Frontiers in Aging Neuroscience (2015) IF: 4.504
    PGC-1α Silencing Compounds The Perturbation Of Mitochondrial Function Caused By Mutant SOD1 In Skeletal Muscle Of ALS Mouse Model.

    DOI: 10.3389/fnagi.2015.00204

    PMID: 26539112

    Sample: Serum
  52. Life Sciences (2020) IF: 3.647
    Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways

    DOI: 10.1016/j.lfs.2020.118546

    PMID: 33035580

    Sample: Serum
  53. Life Sciences (2020) IF: 3.647
    Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE

    DOI: 10.1016/j.lfs.2020.118222

    PMID: 32768577

    Sample: Serum
  54. International Immunopharmacology (2020) IF: 3.943
    miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway

    DOI: 10.1016/j.intimp.2020.107016

    PMID: 33039954

    Sample: Serum
  55. International Immunopharmacology (2020) IF: 3.943
    COX-2-PGE 2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice

    DOI: 10.1016/j.intimp.2020.106801

    PMID: 32702600

    Sample: Tissue homogenate
  56. European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
    miR-181-5p protects mice from sepsis via repressing HMGB1 in an experimental model

    DOI: 10.26355/eurrev_202009_23063

    PMID: 33015817

    Sample: Serum
  57. European Journal of Pharmacology (2020) IF: 3.263
    Glucagon-like peptide-1 cleavage product GLP-1(9-36) reduces neuroinflammation from stroke via the activation of insulin-like growth factor 1 receptor in astrocytes

    DOI: 10.1016/j.ejphar.2020.173581

    PMID: 32949596

    Sample: Cell culture supernatant
  58. Biomolecules & Therapeutics (2020) IF: 3.47
    Antineuroinflammatory Effects of 7,3',4'-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression

    DOI: 10.4062/biomolther.2020.093

    PMID: 32812529

    Sample: Cell culture supernatant
  59. American Journal of Translational Research (2020) IF: 3.375
    Overexpression of lncRNA Gm43050 alleviates apoptosis and inflammation response induced by sevoflurane treatment by regulating miR-640/ZFP91

    PMID: 32913509

    Sample: Cell culture supernatant
  60. Journal of Drug Targeting (2020) IF: 3.38
    Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer's disease in intracerebroventricular streptozotocin model for brain delivery

    DOI: 10.1080/1061186X.2020.1817041

    PMID: 32876502

    Sample: Tissue homogenate
  61. Journal of Biochemical and Molecular Toxicology (2020) IF: 3.606
    Protective roles and mechanisms of rosmarinic acid in cyclophosphamide-induced premature ovarian failure

    DOI: 10.1002/jbt.22591

    PMID: 32711407

    Sample: Serum
  62. Neurochemical Research (2020) IF: 3.038
    Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage

    DOI: 10.1007/s11064-020-03012-3

    PMID: 32170675

    Sample: Tissue homogenate
  63. International Immunopharmacology (2020) IF: 3.943
    Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway

    DOI: 10.1016/j.intimp.2020.106287

    PMID: 32058932

    Sample: Tissue homogenate
  64. IUBMB life (2020) IF: 3.244
    Blockade of high mobility group box 1 involved in the protective of curcumin on myocardial injury in diabetes in vivo and in vitro

    DOI: 10.1002/iub.2226

    PMID: 31909882

    Sample: Serum
  65. International Immunopharmacology (2020) IF: 3.943
    Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation

    DOI: 10.1016/j.intimp.2019.106181

    PMID: 31926446

    Sample: Cell sample,Tissue homogenate
  66. Chemico-Biological Interactions (2020) IF: 3.723
    Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis

    DOI: 10.1016/j.cbi.2019.108891

    PMID: 31697926

    Sample: Plasma,Tissue homogenate
  67. Food & Nutrition Research (2020) IF: 3.647
    Camellia cake extracts reduce burn injury through suppressing inflammatory responses and enhancing collagen synthesis

    DOI: 10.29219/fnr.v64.3782

    PMID: 32425739

    Sample: Tissue homogenate
  68. Psychopharmacology (2020) IF: 3.13
    The protective effect of Geniposide on diabetic cognitive impairment through BTK/TLR4/NF-κB pathway

    DOI: 10.1007/s00213-019-05379-w

    PMID: 31811349

    Sample: Serum
  69. Scientific reports (2020) IF: 3.998
    Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

    DOI: 10.1038/s41598-020-66789-x

    PMID: 32555320

    Sample: Serum
  70. Journal of Functional Foods (2020) IF: 3.701
    Anti-fatigue activity of purified anthocyanins prepared from purple passion fruit (P. edulis Sim) epicarp in mice

    DOI: 10.1016/j.jff.2019.103725

    Sample: Tissue homogenate
  71. Frontiers in Endocrinology (2020) IF: 3.644
    The Protective Effects of Melatonin Against LPS-Induced Septic Myocardial Injury: A Potential Role of AMPK-Mediated Autophagy

    DOI: 10.3389/fendo.2020.00162

    PMID: 32373063

    Sample: Serum
  72. European journal of pharmacology (2019) IF: 3.263
    Circular RNA expression profile of liver tissues in an EtOH-induced mouse model of alcoholic hepatitis

    DOI: 10.1016/j.ejphar.2019.172642

    PMID: 31493407

    Sample: Serum,Tissue homogenate
  73. International immunopharmacology (2019) IF: 3.943
    Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation

    DOI: 10.1016/j.intimp.2019.105915

    PMID: 31639617

    Sample: Serum,Cell culture supernatant
  74. European journal of pharmacology (2019) IF: 3.263
    Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway

    DOI: 10.1016/j.ejphar.2019.172723

    PMID: 31586632

    Sample: Plasma,Cell culture supernatant,Tissue homogenate
  75. American Journal of Translational Research (2019) IF: 3.375
    Xiaoyaosan prevents atherosclerotic vulnerable plaque formation through heat shock protein/glucocorticoid receptor axis-mediated mechanism

    PMID: 31632527

    Sample: Serum
  76. AM J PHYSIOL-RENAL (2020) IF: 3.323
    Inhibition of PDE4/PDE4B Improves Renal Function and Ameliorates Inflammation in Cisplatin-Induced Acute Kidney Injury

    DOI: 10.1152/ajprenal.00477.2019

    PMID: 31961716

    Sample: Serum
  77. International Immunopharmacology (2020) IF: 3.361
    10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells

    DOI: 10.1016/j.intimp.2020.106501

    Sample: Cell culture supernatant
  78. Frontiers in pharmacology (2018) IF: 3.831
    Emodin attenuates lipopolysaccharide-induced acute liver injury through inhibiting the TLR4 signaling pathway in vitro and in vivo

    DOI: 10.3389/fphar.2018.00962

    PMID: 30186181

    Sample: Cell culture supernatant
  79. Bioorganic chemistry (2019) IF: 3.929
    Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer's disease

    DOI: 10.1016/j.bioorg.2018.10.073

    PMID: 30448726

    Sample: Cell culture medium
  80. Fish & shellfish immunology (2019) IF: 3.185
    Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl) thio) isoquinoline in RAW264. 7 macrophages and a zebrafish model

    DOI: 10.1016/j.fsi.2019.01.030

    PMID: 30685466

    Sample: Cell culture supernatant
  81. Toxicology and applied pharmacology (2019) IF: 3.616
    SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress

    DOI: 10.1016/j.taap.2018.10.013

    PMID: 30336174

    Sample: Serum,Tissue homogenate
  82. Molecules (2018) IF: 3.098
    Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264. 7 Cells

    DOI: 10.3390/molecules23102723

    PMID: 30360404

    Sample: Cell culture supernatant
  83. International journal of molecular sciences (2019) IF: 3.687
    Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways

    DOI: 10.3390/ijms20051103

    PMID: 30836660

    Sample: Serum
  84. Toxicology (2019) IF: 3.265
    4-Methylcoumarin-[5,6–g]-hesperetin attenuates inflammatory responses in alcoholic hepatitis through PPAR-γ activation

    DOI: 10.1016/j.tox.2019.04.004

    PMID: 30951781

    Sample: Serum,Cell culture supernatant
  85. Life Sciences (2020) IF: 3.647
    Pretreatment of exosomes derived from hUCMSCs with TNF-α ameliorates acute liver failure by inhibiting the activation of NLRP3 in macrophage

    DOI: 10.1016/j.lfs.2020.117401

    PMID: 32035931

    Sample: Whole Blood,Tissue homogenate
  86. Frontiers in Pharmacology (2019) IF: 3.845
    Ameliorative Effects of Suhuang Antitussive Capsule on LPS-Induced Sputum Obstruction in Mice through Promoting HGF Secretion via an Intestinal Endocrine-Dependent Pathway

    DOI: 10.3389/fphar.2019.01422

    Sample: Serum,Tissue homogenate
  87. Molecules (2019) IF: 3.06
    Design, Synthesis and Investigation of the Potential Anti-inflammatory Activity of 7-O-Amide Hesperetin Derivatives

    DOI: 10.3390/molecules24203663

    PMID: 31614601

    Sample: Cell culture supernatant
  88. Biomedicine & Pharmacotherapy (2018) IF: 3.457
    The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice.

    DOI: 10.1016/j.biopha.2018.07.063

    PMID: 30119194

    Sample: Serum,Tissue homogenate
  89. Neuroscience (2017) IF: 3.277
    Blocking The CD38/cADPR Pathway Plays A Double-edged Role In LPS Stimulated Microglia.

    DOI: 10.1016/j.neuroscience.2017.08.010

    PMID: 28807785

    Sample: Cell culture supernatant
  90. Acta Pharmacologica Sinica (2017) IF: 3.223
    Osthole Prevents Acetaminophen-Induced Liver Injury In Mice.

    DOI: 10.1038/aps.2017.129

    PMID: 29022574

    Sample: Tissue homogenate
  91. Innate Immunity (2021) IF: 2.68
    Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways

    DOI: 10.1177/17534259211051069

    PMID: 34806444

    Sample: Bronchoalveolar Lavage Fluid
  92. Fitoterapia (2021) IF: 2.88
    Structure elucidation and anti-inflammatory mechanism of difengpienol C, a new neolignan isolated from Illicium difengpi

    DOI: 10.1016/j.fitote.2021.104949

    PMID: 34087408

    Sample: Cell culture supernatant
  93. Journal of Neuroscience Methods (2020) IF: 2.214
    Frequent exposure to varied home cage sizes alters pain sensitivity and some key inflammation-related biomarkers

    DOI: 10.1016/j.jneumeth.2020.108890

    PMID: 32768413

    Sample: Tissue homogenate
  94. Bioscience Reports (2020) IF: 2.942
    Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation

    DOI: 10.1042/BSR20192800

    PMID: 32490526

    Sample: Cell culture supernatant
  95. Molecular Medicine Reports (2020) IF: 2.1
    Osthole inhibits proliferation of kainic acid-activated BV-2 cells by modulating the Notch signaling pathway

    DOI: 10.3892/mmr.2020.11455

    PMID: 33000274

    Sample: Cell culture supernatant
  96. Molecular Medicine Reports (2020) IF: 2.1
    Astaxanthin suppresses lipopolysaccharide-induced myocardial injury by regulating MAPK and PI3K/AKT/mTOR/GSK3β signaling

    DOI: 10.3892/mmr.2020.11443

    PMID: 32945516

    Sample: Serum
  97. Brain and behavior (2020) IF: 2.091
    MicroRNA-345-5p regulates depression by targeting suppressor of cytokine signaling 1

    DOI: 10.1002/brb3.1653

    PMID: 32730696

    Sample: Cell culture supernatant
  98. Microbial Pathogenesis (2020) IF: 2.914
    Curcumin ameliorates Staphylococcus aureus-induced mastitis injury through attenuating TLR2-mediated NF-κB activation

    DOI: 10.1016/j.micpath.2020.104054

    PMID: 32061917

    Sample: Serum
  99. Molecular Medicine Reports (2020) IF: 2.1
    Coenzyme Q10 alleviates sevoflurane-induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

    DOI: 10.3892/mmr.2020.11131

    PMID: 32377738

    Sample: Tissue homogenate
  100. Poultry science (2019) IF: 2.659
    Anti-inflammatory effect of preserved egg with simulated gastrointestinal digestion on LPS-stimulated RAW264.7 cells

    DOI: 10.3382/ps/pez243

    PMID: 31041437

    Sample: Cell culture supernatant
  101. Molecular medicine reports (2018) IF: 2.1
    Dioscin prevents LPS-induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70

    DOI: 10.3892/mmr.2018.8667

    PMID: 29512786

    Sample: Serum,Tissue homogenate
  102. Medicine (2018) IF: 2.028
    Effect of gap junctions on RAW264. 7 macrophages infected with H37Rv

    DOI: 10.1097/MD.0000000000012125

    PMID: 30170447

    Sample: Cell culture supernatant
  103. Inflammation (2018) IF: 2.884
    miR-590-3p Attenuates Acute Kidney Injury by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 in Septic Mice

    DOI: 10.1007/s10753-018-0921-5

    PMID: 30392071

    Sample: Serum
  104. Bioscience reports (2018) IF: 2.899
    Maggot protein ameliorates dextran sulphate sodium-induced ulcerative colitis in mice

    DOI: 10.1042/BSR20181799

    PMID: 30393231

    Sample: Serum
  105. Biochemical and biophysical research communications (2019) IF: 2.559
    Eosinophils attenuate arthritis by inducing M2 macrophage polarization via inhibiting the IkB/P38 MAPK signaling pathway

    DOI: 10.1016/j.bbrc.2018.12.010

    PMID: 30528734

    Sample: Tissue homogenate,Cell culture supernatant
  106. Inflammation (2018) IF: 2.884
    Resveratrol Protects Against Renal Damage via Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice

    DOI: 10.1007/s10753-018-0948-7

    PMID: 30554371

    Sample: Tissue homogenate
  107. Bioscience reports (2018) IF: 2.899
    Association of IL-6, IL-8, MMP-13 gene polymorphisms with knee osteoarthritis susceptibility in the Chinese Han population

    DOI: 10.1042/BSR20181346

    PMID: 30635366

    Sample: Tissue homogenate
  108. Steroids (2019) IF: 2.523
    Synthesis and Evaluation of Novel D-ring Substituted Steroidal Pyrazolines as Potential Anti-inflammatory Agents

    DOI: 10.1016/j.steroids.2019.03.012

    PMID: 30951758

    Sample: Cell culture supernatant
  109. Journal of the Science of Food and Agriculture (2019) IF: 2.379
    Effect and mechanism of citral against methicillin-resistant Staphylococcus aureus in vivo

    DOI: 10.1002/jsfa.9677

    PMID: 30891759

    Sample: Serum
  110. Journal of cellular biochemistry (2019) IF: 2.959
    Attractylone Attenuates Sepsis-Associated Encephalopathy and Cognitive Dysfunction by Inhibiting Microglial Activation and Neuroinflammation

    DOI: 10.1002/jcb.27983

    PMID: 30672013

    Sample: Cell culture supernatant,Tissue homogenate
  111. Gene (2019) IF: 2.498
    The inhibition of microRNA-203 on ischemic reperfusion injury after total knee arthroplasty via suppressing MYD88-mdiated toll-like receptor signaling pathway

    DOI: 10.1016/j.gene.2019.02.030

    PMID: 30772517

    Sample: Tissue homogenate
  112. Inflammation (2019) IF: 2.884
    Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

    DOI: 10.1007/s10753-019-00986-3

    PMID: 30847744

    Sample: Serum,Cell culture supernatant
  113. Biomedical and Environmental Sciences (2018) IF: 2.518
    Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice.

    DOI: 10.3967/bes2018.101

    PMID: 30423277

    Sample: Plasma,Tissue homogenate
  114. Plos One (2017) IF: 2.806
    Therapeutic Effect Of imiquimod On Dextran Sulfate Sodium-induced Ulcerative Colitis In Mice.

    DOI: 10.1371/journal.pone.0186138

    PMID: 29049372

    Sample: Serum
  115. PloS one (2017) IF: 2.806
    Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet.

    DOI: 10.1371/journal.pone.0185688

    PMID: 28961281

    Sample: Serum
  116. International Immunopharmacology (2017) IF: 2.956
    Wogonin Attenuates Inflammation By Activating PPAR-γ In Alcoholic Liver Disease.

    DOI: 10.1016/j.intimp.2017.06.013

    PMID: 28646664

    Sample: Serum,Cell culture supernatant
  117. Molecules (2017) IF: 2.861
    Capparis Spinosa Fruit Ethanol Extracts Exert Different Effects On The Maturation Of Dendritic Cells.

    DOI: 10.3390/molecules22010097

    PMID: 28067853

    Sample: Cell culture supernatant
  118. Biochemical & Biophysical Research Communications (2015) IF: 2.466
    Ghrelin Ameliorates Intestinal Barrier Dysfunction In Experimental Colitis By Inhibiting The Activation Of Nuclear Factor-Kappa B.

    DOI: 10.1016/j.bbrc.2015.01.083

    PMID: 25634696

    Sample: Tissue homogenate
  119. Food Science & Nutrition (2020) IF: 1.797
    Subcutaneous administration of casein attenuates atherosclerotic progression in male apoE -/- mice fed with high-fat diet

    DOI: 10.1002/fsn3.1638

    PMID: 32724618

    Sample: Plasma
  120. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate-induced colitis

    DOI: 10.3892/etm.2020.9138

    PMID: 32934675

    Sample: Serum
  121. Current Medical Science (2020) IF: 1.273
    Role of Interleukin 17A in Aortic Valve Inflammation in Apolipoprotein E-deficient Mice

    DOI: 10.1007/s11596-020-2230-0

    PMID: 32862384

    Sample: Plasma
  122. Asian Pacific Journal of Tropical Medicine (2019) IF: 1.94
    Alpinia officinarum Hance extract alleviates particulate matter-induced lung injury in mice

    DOI: 10.4103/1995-7645.272487

    Sample: Serum,Bronchoalveolar Lavage Fluid,Tissue homogena
  123. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research (2020) IF: 1.918
    The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid

    DOI: 10.12659/MSM.919220

    PMID: 32026851

    Sample: Serum,Cell culture supernatant,Tissue homogenate
  124. Current medical science (2019) IF: 1.273
    Berberine Attenuates Cigarette Smoke Extract-induced Airway Inflammation in Mice: Involvement of TGF-β1/Smads Signaling Pathway

    DOI: 10.1007/s11596-019-2101-8

    PMID: 31612392

    Sample: Bronchoalveolar Lavage Fluid
  125. Canadian journal of physiology and pharmacology (2019) IF: 1.946
    Role of Brd4 in the production of inflammatory cytokines in mouse macrophages treated with titanium particles

    DOI: 10.1139/cjpp-2019-0142

    PMID: 31330113

    Sample: Cell culture supernatant
  126. Experimental and therapeutic medicine (2018) IF: 1.41
    miR-148a inhibits pro-inflammatory cytokines released by intervertebral disc cells by regulating the p38/MAPK pathway

    DOI: 10.3892/etm.2018.6516

    PMID: 30186499

    Sample: Cell culture supernatant
  127. Medical molecular morphology (2019) IF: 1.217
    The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression

    DOI: 10.1007/s00795-019-00216-7

    PMID: 30673851

    Sample: Serum,Tissue homogenate
  128. Cellular & molecular biology letters (2019) IF: 1.291
    Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling

    DOI: 10.1186/s11658-018-0125-x

    PMID: 30820195

    Sample: Cell culture supernatant
  129. Journal of biochemical and molecular toxicology (2019) IF: 1.837
    Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats

    DOI: 10.1002/jbt.22302

    PMID: 30790395

    Sample: Serum,Tissue homogenate
  130. Cellular & molecular biology letters (2019) IF: 1.291
    Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

    DOI: 10.1186/s11658-019-0142-4

    PMID: 30833971

    Sample: Serum
  131. Reproduction, Fertility and Development (2019) IF: 1.723
    Notch signalling regulates steroidogenesis in mouse ovarian granulosa cells

    DOI: 10.1071/RD18281

    PMID: 30827331

    Sample: Cell culture medium
  132. Oncology Letters (2018) IF: 1.39
    The Association Between Inflammation, The Microbiome and Urethane-induced Pulmonary Adenocarcinoma.

    DOI: 10.3892/ol.2018.8167

    PMID: 29725395

  133. Molecular Medicine Reports (2018) IF: 1.692
    Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses.

    DOI: 10.3892/mmr.2018.8767

    PMID: 29568928

  134. International Journal of Clinical and Experimental Pathology (2015) IF: 1.706
    An Unusual Case Of Iron Deficiency Anemia Is Associated With Extremely Low Level Of Transferrin Receptor.

    PMID: 26339443

    Sample: Serum
  135. International Journal of Clinical and Experimental Medicine (2015) IF: 1.069
    Sulfated Modification Promotes The Immunomodulatory Bioactivities Of Lyciumbarbarum Polysaccharides In Vitro.

    PMID: 26884954

    Sample: Cell culture supernatant
  136. Journal of Oleo Science (2015) IF: 1.076
    A Comparative Study Of The Effects Upon LPS Induced Macrophage RAW264.7 Inflammation In Vitro Of The Lipids Of Hippocampus Trimaculatus Leach.

    DOI: 10.5650/jos.ess15190

    PMID: 26582156

    Sample: Cell culture supernatant
  137. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research (2020)
    Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis

    DOI: 10.1016/j.toxlet.2020.07.028

    PMID: 32768653

    Sample: Cell culture supernatant,Tissue homogenate
  138. Advances in Pharmacological and Pharmaceutical Sciences (2020)
    Antihypernociceptive, Anxiolytic, and Antidepressant Properties of Aqueous and Ethanol Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Mice

    DOI: 10.1155/2020/8886894

    PMID: 33015629

    Sample: Serum,Tissue homogenate
  139. The FASEB Journal (2020)
    CaMK4-dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis

    DOI: 10.1096/fj.201902910RRR

    PMID: 32862457

    Sample: Cell culture supernatant,Tissue homogenate
  140. Jurnal Kedokteran Brawijaya (2020)
    The Effects of Thyme on IL-6 Level and the Bacterial Count in the Brain and Spleen of Mice Infected by Methicillin-Resistant Staphylococcus aureus (MRSA)

    DOI: 10.21776/ub.jkb.2020.031.01.1

    Sample: Plasma
  141. bioRxiv (2020)
    Fecal microbiota transplantation reconstructs the gut microbiota of septic mice and protects the intestinal mucosal barrier

    DOI: 10.1101/2020.06.22.164541

    Sample: Serum
  142. SSRN (2020)
    Salidroside Attenuates Liver Injury in Diabetes Mice

    DOI: 10.2139/ssrn.3546025

    Sample: Serum,Cell culture supernatant,Tissue homogenate
  143. Journal of Cellular and Molecular Medicine (2020)
    Polysaccharides from Dicliptera chinensis ameliorate liver disturbance by regulating TLR-4/NF-κB and AMPK/Nrf2 signalling pathways

    DOI: 10.1111/jcmm.15286

    PMID: 32337831

    Sample: Serum,Tissue homogenate
  144. Open access Macedonian journal of medical sciences (2019)
    Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice

    DOI: 10.3889/oamjms.2019.247

    PMID: 31049081

    Sample: Tissue homogenate
  145. Veterinary world (2019)
    Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle

    DOI: 10.14202/vetworld.2019.684-688

    PMID: 31327904

    Sample: Tissue homogenate
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R*********sSubmitted [ Jul 05 2021 ]

Asked: Hello, Is E-EL-M0044 kit suitable for tissue homogenates?



adminSubmitted [ Jul 05 2021 ]

Answered: The E-EL-M0044 kit is suitable for mouse tissue homogenates samples.


adminSubmitted [ Jul 05 2021 ]


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