Mouse TRAIL/TNFSF10 Antibody Pair Set (E-KAB-0562)
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For research use only.
| Background |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain , but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis , and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines , which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
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| Synonyms |
APO2L, Apo2-L, TL2, CD253
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse TRAIL/TNFSF10 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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