MSN Polyclonal Antibody

Uniprot : P26038
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14222

      Synonyms:Epididymis luminal protein 70,HEL70,Membrane organizing extension spike protein,Membrane-organizing extension spike protein,MOES,Moesin,Moesin/anaplastic lymphoma kinase fusion protein,Msn,MSN/ALK fusion

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Epididymis luminal protein 70,HEL70,Membrane organizing extension spike protein,Membrane-organizing extension spike protein,MOES,Moesin,Moesin/anaplastic lymphoma kinase fusion protein,Msn,MSN/ALK fusion
      Swissprot P26038
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human MSN
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
      Concentration 0.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Cytoplasm>cytoskeleton. Apical cell membrane. Cell projection>microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.
      Tissue specificity In all tissues and cultured cells studied.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.

      Images

      Western Blot analysis of 293T and A431 cell using MSN Polyclonal Antibody at dilution of 1:500

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using MSN Polyclonal Antibody at dilution of 1:30

      Immunohistochemistry of paraffin-embedded Human ovarian cancer using MSN Polyclonal Antibody at dilution of 1:30

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