NAE1 Polyclonal Antibody

Uniprot : Q13564
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14592

      Synonyms:59 kDa,A 116A10.1,Amyloid beta precursor protein binding protein 1 59kD,Amyloid beta precursor protein binding protein 1 59kDa,Amyloid beta precursor protein binding protein 1,Amyloid beta precursor protein binding protein 1,59 kDa,Amyloid beta precursor protein-binding protein 1,Amyloid protein binding protein 1,Amyloid protein-binding protein 1,APP BP1,APP-BP1,APPBP 1,APPBP1,HPP 1,HPP1,NAE 1,NAE1,NEDD8 activating enzyme E1 regulatory subunit,NEDD8 activating enzyme E1 subunit 1,NEDD8 activating enzyme E1 subunit,NEDD8-activating enzyme E1 regulatory subunit,Proto oncogene protein 1,Proto-oncogene protein 1,Protooncogene protein 1,ula 1,ULA1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 59 kDa,A 116A10.1,Amyloid beta precursor protein binding protein 1 59kD,Amyloid beta precursor protein binding protein 1 59kDa,Amyloid beta precursor protein binding protein 1,Amyloid beta precursor protein binding protein 1,59 kDa,Amyloid beta precursor protein-binding protein 1,Amyloid protein binding protein 1,Amyloid protein-binding protein 1,APP BP1,APP-BP1,APPBP 1,APPBP1,HPP 1,HPP1,NAE 1,NAE1,NEDD8 activating enzyme E1 regulatory subunit,NEDD8 activating enzyme E1 subunit 1,NEDD8 activating enzyme E1 subunit,NEDD8-activating enzyme E1 regulatory subunit,Proto oncogene protein 1,Proto-oncogene protein 1,Protooncogene protein 1,ula 1,ULA1
      Swissprot Q13564
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human NAE1
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Colocalizes with APP in lipid rafts.
      Tissue specificity Ubiquitous in fetal tissues. Expressed throughout the adult brain.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of Human fetal muscle, kidney and liver tissue using NAE1 Polyclonal Antibody at dilution of 1:500

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