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NEK2 Polyclonal Antibody

Cat:E-AB-10922
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB
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Product Details
Verified Samples Verified Samples in WB:LoVo
Dilution

WB 1:500-1:2000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human NEK2
Abbre NEK2
Synonyms HSPK 21;HsPK21;NEK 2;NEK2;NEK2;NEK2A;Never in mitosis A-related kinase 2;NIMA (never in mitosis gene a) related kinase 2;NimA like protein kinase 1;NIMA related kinase 2;NimA related protein kinase 2;NimA-like protein kinase 1;NimA-related protein kinase 2;NLK 1;NLK1;Serine/threonine-protein kinase Nek2
Swissprot
Calculated MW 52kDa
Cellular Localization Cytoplasm. Predominantly cytoplasmic; Nucleus>nucleolus. Has a nucleolar targeting/ retention activity via a coiled-coil domain at the C-terminal end and Nucleus. Chromosome>centromere. Chromosome>centromere>kinetochore. Co-localizes with SGOL1 and MAD1L1 at the kinetochore. Not associated with kinetochore in the interphase but becomes associated with it upon the breakdown of the nuclear envelope.
Concentration 0.3 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.