Neuraminidases (NA) Inhibitor Screening Assay Kit (E-BC-D004)
For research use only.
| Detection Principle | Neuraminidases, also known as sialidase, are a family of exoglycans that hydrolyse glycolipids, oligosaccharides and sialic acid residues at the end of glycoproteins. NA is distributed in viruses, bacteria, fungi and vertebrate cells. Viral neuraminidase is one of the important targets of some influenza drugs. Human neuraminidase plays a role in a variety of signaling pathways and is associated with a variety of diseases such as neurodegenerative diseases, cancer, and cardiovascular and cerebrovascular diseases. Therefore, it is important to develop NA inhibitors. The detection principle of this kit is that NA decomsolves the substrate to release fluorescent substances, and the activity can be inhibited by adding NA inhibitor. The inhibition ability of inhibitor can be judged by the fluorescence value. |
| Synonyms | NA |
| Sample Type | Inhibitor |
| Detection Method | Fluorometric method |
| Detection Instrument | Fluorescence microplate reader (Ex/Em=330 nm/450 nm) |
| Research Area | Inhibitor Screening |
| Storage | This product can be stored at -20°C for 12 months with shading light. |
| Valid Period | 12 months |
| Precision | inter-assay CV: 2.0-4.0% | intra-assay CV: 1.0-2.0% |
| Sample Volume | 20 μL |
| Assay Time | 1 h |
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