NFkB p100 / p52 Polyclonal Antibody (E-AB-60843)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat brain, Human breast, Mouse testis Verified Samples in IF: U2OS |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human NFkB p100 / p52 (NP_002493.3). |
| Abbre | NFkB p100 / p52 |
| Synonyms | CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52 |
| Swissprot | |
| Cellular Localization | Cytoplasmic and Nuclear. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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