NLRP6 Polyclonal Antibody (E-AB-16629)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NLRP6 |
| Abbre | NLRP6 |
| Synonyms | AVR, Angiotensin II/vasopressin receptor, CLR11.4, LRR and PYD containing protein 6, LRR and PYD domains-containing protein 6, NACHT, NAVR, NAVR/AVR, NLR family, NLRP6, Nlrp6, Nucleotide , leucine rich repeat and PYD containing 6, pyrin domain containing 6 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Inflammasome. Cell membrane. Nucleus membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Immunology, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. |
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