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NOD1 Polyclonal Antibody

Cat:E-AB-13110
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human liver cancer,Human lung cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human NOD1
Abbre NOD1
Synonyms CARD 4;CARD4;Caspase recruitment domain 4;Caspase recruitment domain containing protein 4;Caspase recruitment domain family member 4;Caspase recruitment domain protein 4;Caspase recruitment domain-containing protein 4;CLR 7.1;CLR7.1;NLR family CARD domain containing 1;NLRC 1;NLRC1;NOD 1;Nod1;NOD1 protein;NOD1;Nucleotide binding oligomerization domain containing 1;Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1;Nucleotide-binding oligomerization domain-containing protein 1;Protein Nod1
Swissprot
Cellular Localization Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Detected in the cytoplasm and at the cell membrane. Following bacterial infection, localizes to bacterial entry sites in the cell membrane. Recruited to the basolateral and apical membranes in polarized epithelial cells.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.