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PAK2 Polyclonal Antibody

Cat:E-AB-10521
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human thyroid cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human PAK2
Abbre PAK2
Synonyms C-t-PAK2;CB422;EC 2.7.11.1;Gamma PAK;Gamma-PAK;hPAK65;Kinase;p21 (CDKN1A) activated kinase 2;p21 (CDKN1A)-activated kinase 2a;p21 activated kinase 2;p21 protein (Cdc42/Rac)-activated kinase 2;p21 protein Cdc42 Rac activated kinase 2;p21-activated kinase 2;p21-activated kinase;65-KD;p21-activated protein kinase I;p21CDKN1A activated kinase 2;p27;p34;p58;p65PAK;PAK 2;PAK-2;PAK-2p34;Pak2;PAK2;PAK65;PAKgamma;S6 H4 kinase;S6/H4 kinase;Serine threonine protein kinase PAK 2;Serine/threonine protein kinase PAK 2
Swissprot
Cellular Localization Cytoplasm and Nucleus. Cytoplasm>perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.
Concentration 0.6 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology; Microbiology; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.