PAK2 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human thyroid cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PAK2 |
Abbre | PAK2 |
Synonyms | C-t-PAK2;CB422;EC 2.7.11.1;Gamma PAK;Gamma-PAK;hPAK65;Kinase;p21 (CDKN1A) activated kinase 2;p21 (CDKN1A)-activated kinase 2a;p21 activated kinase 2;p21 protein (Cdc42/Rac)-activated kinase 2;p21 protein Cdc42 Rac activated kinase 2;p21-activated kinase 2;p21-activated kinase;65-KD;p21-activated protein kinase I;p21CDKN1A activated kinase 2;p27;p34;p58;p65PAK;PAK 2;PAK-2;PAK-2p34;Pak2;PAK2;PAK65;PAKgamma;S6 H4 kinase;S6/H4 kinase;Serine threonine protein kinase PAK 2;Serine/threonine protein kinase PAK 2 |
Swissprot | |
Cellular Localization | Cytoplasm and Nucleus. Cytoplasm>perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane. |
Concentration | 0.6 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Microbiology; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol