PARD6A Polyclonal Antibody

Uniprot : Q9NPB6
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14283

      Synonyms:0710008C04Rik,2610010A15Rik,Par 6 partitioning defective 6 C elegans homolog alpha,Par 6 partitioning defective 6 homolog alpha,Par 6 partitioning defective 6 homolog alpha C elegans,PAR 6A,PAR-6 alpha,PAR-6,par-6 family cell polarity regulator alpha,PAR-6A,PAR6,PAR6A,PAR6alpha,PAR6C,Pard6a,Partitioning defective 6 homolog alpha,partitioning-defective protein 6,partitioning-defective protein 6, C. elegans,homolog of,alpha,Tax interacting protein 40,Tax interaction protein 40,TAX40,TIP 40,TIP-40,TIP40

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 0710008C04Rik,2610010A15Rik,Par 6 partitioning defective 6 C elegans homolog alpha,Par 6 partitioning defective 6 homolog alpha,Par 6 partitioning defective 6 homolog alpha C elegans,PAR 6A,PAR-6 alpha,PAR-6,par-6 family cell polarity regulator alpha,PAR-6A,PAR6,PAR6A,PAR6alpha,PAR6C,Pard6a,Partitioning defective 6 homolog alpha,partitioning-defective protein 6,partitioning-defective protein 6, C. elegans,homolog of,alpha,Tax interacting protein 40,Tax interaction protein 40,TAX40,TIP 40,TIP-40,TIP40
      Swissprot Q9NPB6
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PARD6A
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.7 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Cell membrane. Cell projection>ruffle. Cell junction>tight junction. Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions.
      Tissue specificity Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

      Images

      Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60

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