PDCD4 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human; Mouse; Rat
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human ovarian cancer,Human tonsil |
Dilution |
IHC 1:40-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Fusion protein of human PDCD4 |
Abbre | PDCD4 |
Synonyms | Death up-regulated gene protein;Dug;H731;Ma3;MGC33046;MGC33047;Neoplastic transformation inhibitor;Neoplastic transformation inhibitor protein;Nuclear antigen H731;Nuclear antigen H731 like;Nuclear antigen H731 like protein;Nuclear antigen H731-like;PDCD 4;Pdcd4;PDCD4;Programmed cell death 4;programmed cell death 4 (neoplastic transformation inhibitor);Programmed cell death protein 4;Protein 197/15a;Protein MA-3;Tis;Topoisomerase-inhibitor suppressed protein |
Swissprot | |
Cellular Localization | Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457. Exported from the nucleus in the absence of serum. |
Concentration | 0.6 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol