PDCD6 Polyclonal Antibody

Uniprot : O75340
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14287

      Synonyms:AIP1,ALG 2,ALG-2-interacting protein 1,ALG2,ALIX,Apoptosis linked gene 2,Apoptosis linked gene 2 protein,Apoptosis-linked gene 2 protein,FLJ42309,FLJ46208,Hp95,KIAA1375,MA 3,MA3,MGC111017,MGC119050,MGC9123,PDCD 6,Pdcd6,PDCD6,PEF 1B,PEF1B,Probable calcium binding protein ALG 2,Probable calcium binding protein ALG2,Probable calcium-binding protein ALG-2,Programmed cell death 6,Programmed cell death 6-interacting protein,Programmed cell death protein 6,PS 2,PS2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AIP1,ALG 2,ALG-2-interacting protein 1,ALG2,ALIX,Apoptosis linked gene 2,Apoptosis linked gene 2 protein,Apoptosis-linked gene 2 protein,FLJ42309,FLJ46208,Hp95,KIAA1375,MA 3,MA3,MGC111017,MGC119050,MGC9123,PDCD 6,Pdcd6,PDCD6,PEF 1B,PEF1B,Probable calcium binding protein ALG 2,Probable calcium binding protein ALG2,Probable calcium-binding protein ALG-2,Programmed cell death 6,Programmed cell death 6-interacting protein,Programmed cell death protein 6,PS 2,PS2
      Swissprot O75340
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human PDCD6
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

      Images

      Western Blot analysis of Jurkat and hela cell, Human fetal lung tissue and A549 cell using PDCD6 Polyclonal Antibody at dilution of 1:200

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using PDCD6 Polyclonal Antibody at dilution of 1:30

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