PDE5A Polyclonal Antibody (E-AB-16696)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human breast cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PDE5A |
| Abbre | PDE5A |
| Synonyms | 5''-cyclic phosphodiesterase, CGB PDE, CGB-PDE, CGBPDE, cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase, cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase, cGMP binding cGMP specific phosphodiesterase, cGMP binding/cGMP speci |
| Swissprot | |
| Cellular Localization | Cytosol |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Cardiovascular, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. |
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