PDPN Polyclonal Antibody

Uniprot : Q86YL7
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17607

      Synonyms:T1A,GP36,GP40,Gp38,OTS8,T1A2,TI1A,T1A-2,AGGRUS,HT1A-1,PA2.26

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms T1A,GP36,GP40,Gp38,OTS8,T1A2,TI1A,T1A-2,AGGRUS,HT1A-1,PA2.26
      Swissprot Q86YL7
      Source Rabbit
      Reactivity Human
      Immunogen Synthetic peptide of human PDPN
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1000, IHC 1:10-50, ELISA 1:1000-2000
      Concentration 0.3mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane. Cell projection>filopodium membrane. Cell projection>lamellipodium membrane. Cell projection>microvillus membrane. Cell projection>ruffle membrane. Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles.
      Tissue specificity Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25% of early oral squamous cell carcinomas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer using PDPN Polyclonal Antibody at dilution of 1/20

      Western Blot analysis of Human fetal brain tissue, Hela and 293T cells using PDPN Polyclonal Antibody at dilution of 1/200

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