PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] (E-AB-F1192UD)
                        For research use only.
| Alternate Names | TIMD3, HAVcr-2, TIM3, TIMD-3 | 
| Clone No | |
| Leadtime | Order now, ship in 3 days | 
| Background | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. | 
| Abbre | CD366 | 
| Swissprot | |
| Host | Rat | 
| Reactivity | Mouse | 
| Clonality | Monoclonal | 
| Isotype | Rat IgG2a, κ | 
| Isotype Control | E-AB-F09833D | 
| Applications | 
                         
                FCM             
         | 
    
| Research Areas | Immunology;Inhibitory Molecules | 
| Cellular Localization | 
             
                Membrane             
         | 
    
| Form | Liquid | 
| Concentration | 
             
                0.2 mg/mL             
         | 
    
| Conjugation | PE | 
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). | 
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. | 
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. | 
| Expiration Date | 12 months | 
| Shipping | Ice bag | 
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