Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> PE/Cyanine5 Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]
Cat.No.:E-AB-F1114UG
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Alternate Names | C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183/CXCR3 |
Swissprot | O88410 |
References |
1. Krug A, Uppaluri R, Facchetti F, et al. J Immunol. 2002; 169(11):6079-6083.
2. Soto H, Wang W, Strieter RM, et al. Proc Natl Acad Sci U S A. 1998; 95(14):8205-8210. 3. Tamaru M, Tominaga Y, Yatsunami K, Narumi S. Biochem Biophys Res Commun. 1998; 251(1):41-48. |
Form | Liquid |
Clone No. | CXCR3-173(See Other Available Formats) |
Host | Armenian Hamster |
Isotype | Armenian Hamster IgG |
Isotype Control | [Product E-AB-F09853G] |
Reactivity | Mouse |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | PE/Cyanine5 |
PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter). | |
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How to select the appropriate detection channel through the spectrogram?
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
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