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PE/Cyanine7 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155H

Uniprot : Q12918
  • Host: Mouse
  • Applications: FCM
  • Isotype: Mouse IgG1, κ
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Antigen Details

Alternate Names CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1
Swissprot Q12918
References
1. Takahashi T, et al. 2006. J. Immunol. 176:211.
2. Cosmi L, et al. 2008. J. Exp. Med. 205:1903.
3. Aldemir H, et al. 2005. J. Immunol. 175:7791.
4. Rosen DB, et al. 2008. J. Immunol. 180:6508.

Product Details

Form Liquid
Clone No. HP-3G10(See Other Available Formats)
Host Mouse
Isotype Mouse IgG1, κ
Isotype Control PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792H]
Reactivity Human
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation PE/Cyanine7

Background

CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F1155C FITC Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155C 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155D PE Anti-Human CD161 Antibody[HP-3G10] 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155E APC Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155E 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155G PE/Cyanine5 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155G 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155H PE/Cyanine7 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155H 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155I PE/Cyanine5.5 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155I 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155J PerCP/Cyanine5.5 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155J 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155L AF488 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155L 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1155M AF647 Anti-Human CD161 Antibody[HP-3G10] E-AB-F1155M 20 Tests, 50 Tests, 100 Tests, 200 Tests

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