PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody[A7R34] (E-AB-F1023UH)
For research use only.
Conjugation: PE/Cyanine 7
APC Biotin Elab Bright™Violet 421 Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD127 |
| Synonyms | CD127, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, Il7r, Interleukin-7 receptor subunit alpha |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology |
| Clone No. | A7R34 |
| Conjugation | PE/Cyanine 7 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |
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