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PE/Cyanine7 Anti-Mouse CD206 Antibody[C068C2]

Uniprot : Q61830
  • Cat.No.:E-AB-F1135H

  • Reactivity: Mouse

To Purchase E-AB-F1135H

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  • 20Tests
  • 50Tests
  • 100Tests
  • 200Tests
Price: $75
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Antigen Details

Alternate Names MMR,MR,MRC1,macrophage mannose receptor,mannose receptor
Swissprot Q61830

Product Details

Form Liquid
Clone No. C068C2(See Other Available Formats)
Host Rat
Isotype Rat IgG2a, κ
Isotype Control PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09832H]
Reactivity Mouse
Application ICFCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation PE/Cyanine7

Background

CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F1135C FITC Anti-Mouse CD206 Antibody[C068C2] 20Tests, 50Tests, 100Tests, 200Tests
E-AB-F1135D PE Anti-Mouse CD206 Antibody[C068C2] 20Tests, 50Tests, 100Tests, 200Tests
E-AB-F1135E APC Anti-Mouse CD206 Antibody[C068C2] 20Tests, 50Tests, 100Tests, 200Tests
E-AB-F1135H PE/Cyanine7 Anti-Mouse CD206 Antibody[C068C2] 20Tests, 50Tests, 100Tests, 200Tests
E-AB-F1135UC FITC Anti-Mouse CD206 Antibody[C068C2] 25μg, 50μg, 100μg
E-AB-F1135UD PE Anti-Mouse CD206 Antibody[C068C2] 25μg, 50μg, 100μg
E-AB-F1135UE APC Anti-Mouse CD206 Antibody[C068C2] 25μg, 50μg, 100μg
E-AB-F1135UH PE/Cyanine7 Anti-Mouse CD206 Antibody[C068C2] 25μg, 50μg, 100μg

Citations

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