Alternate Names	Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b
Swissprot	P11215
References	1. Stewart M, et al. 1995. Curr. Opin. Cell Biol. 7:690.

Product Details

Form	Liquid
Clone No.	ICRF44(See Other Available Formats)
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	PerCP Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792F]
Reactivity	Human
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	PerCP
	PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
FITC Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
PE Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
APC Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® Red 780 Anti-Human CD11b Antibody[ICRF44]	20Tests, 100Tests, 100Tests×2	Check More

Citations

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