Alternate Names	Integrin alpha-X,Itgax,CD11 antigen-like family member C,Leukocyte adhesion receptor p150+95,CD11c
Swissprot	Q9QXH4
References	1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press. 2. Springer TA. 1994. Cell 76:301. 3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Product Details

Form	Liquid
Clone No.	N418(See Other Available Formats)
Host	Armenian Hamster
Isotype	Armenian Hamster IgG
Isotype Control	[Product E-AB-F09853F]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	PerCP
	PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
Biotin Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
FITC Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PerCP Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® Violet 450 Anti-Mouse CD11c Antibody[N418]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
PE Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
APC Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
PE/Cyanine5 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
PE/Cyanine5.5 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
PerCP/Cyanine5.5 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
Elab Fluor^® 488 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
Elab Fluor^® 647 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More
Elab Fluor^® Violet 450 Anti-Mouse CD11c Antibody[N418]	25μg, 100μg	Check More

Citations

Marine Drugs (2022) IF: 5.118
In Vitro and In Vivo Dendritic Cell Immune Stimulation Effect of Low Molecular Weight Fucoidan from New Zealand Undaria pinnatifida

DOI: 10.3390/md20030197

PMID: 35323496
Sample: Dendritic cells (DCs)

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