Current Position:Home>>Antibodies>>FCM Antibodies>> PerCP/Cyanine5.5 Anti-Human CD107a/LAMP-1 Antibody[H4A3] E-AB-F1149J
|Alternate Names||Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1|
1. Sarafian V, et al. 2006. Arch. Dermatol. Res. 298:7381.
2. Schlossman SF, et al. 1995. Leukocyte Typing V:White Cell Differentiation Antigens. New York:Oxford University Press.
3. Sawada R, et al. 1993. J. Biol. Chem. 268:12675.
4. Chen JW, et al. 1988. J. Biol. Chem. 263:8754.
5. Chen JW, et al. 1986. Biochem. Soc. Symp. 51:97112.
|Clone No.||H4A3(See Other Available Formats)|
|Isotype||Mouse IgG1, κ|
|Isotype Control||PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792J]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 2 μL or 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F1149C||FITC Anti-Human CD107a/LAMP-1 Antibody[H4A3] E-AB-F1149C||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1149D||PE Anti-Human CD107a/LAMP-1 Antibody[H4A3] E-AB-F1149D||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1149E||APC Anti-Human CD107a/LAMP-1 Antibody[H4A3] E-AB-F1149E||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1149J||PerCP/Cyanine5.5 Anti-Human CD107a/LAMP-1 Antibody[H4A3] E-AB-F1149J||20 Tests, 50 Tests, 100 Tests, 200 Tests|