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PerCP/Cyanine5.5 Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UJ

Uniprot : P04157
  • Host: Mouse
  • Applications: FCM
  • Isotype: Mouse IgG1, κ
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Antigen Details

Alternate Names Receptor-type tyrosine-protein phosphatase C,Leukocyte common antigen, LCA, T200, Ly-5,Ptprc
Swissprot P04157
References
1. Sunderland CA, et al. 1979. Eur. J. Immunol. 9:155.
2. Woolett GR, et al. 1985. Eur. J. Immunol.. 15:168.

Product Details

Form Liquid
Clone No. OX-1(See Other Available Formats)
Host Mouse
Isotype Mouse IgG1, κ
Isotype Control PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09793J]
Reactivity Rat
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution we used in the experiment.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation PerCP/Cyanine5.5

Background

CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F1227C FITC Anti-Rat CD45 Antibody[OX-1] E-AB-F1227C 50 Tests, 100 Tests, 200 Tests, 500 Tests
E-AB-F1227D PE Anti-Rat CD45 Antibody[OX-1] E-AB-F1227D 50 Tests, 100 Tests, 200 Tests, 500 Tests
E-AB-F1227E APC Anti-Rat CD45 Antibody[OX-1] E-AB-F1227E 50 Tests, 100 Tests, 200 Tests, 500 Tests
E-AB-F1227G PE/Cyanine5 Anti-Rat CD45 Antibody[OX-1] E-AB-F1227G 20 Tests, 50 Tests, 100 Tests, 500 Tests
E-AB-F1227J PerCP/Cyanine5.5 Anti-Rat CD45 Antibody[OX-1] E-AB-F1227J 20 Tests, 50 Tests, 100 Tests, 500 Tests
E-AB-F1227UC FITC Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UC 25μg, 50μg, 100μg
E-AB-F1227UD PE Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UD 25μg, 50μg, 100μg
E-AB-F1227UE APC Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UE 25μg, 50μg, 100μg
E-AB-F1227UG PE/Cyanine5 Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UG 25μg, 50μg, 100μg
E-AB-F1227UJ PerCP/Cyanine5.5 Anti-Rat CD45 Antibody[OX-1] E-AB-F1227UJ 25μg, 50μg, 100μg

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