PIP5K1B Polyclonal Antibody

Uniprot : O14986
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14738

      Synonyms:MSS 4,MSS4,Phosphatidylinositol 4 phosphate 5 kinase type 1 beta,Phosphatidylinositol-4-phosphate 5-kinase type I beta,Phosphatidylinositol-4-phosphate 5-kinase type-1 beta,PI4P5K 1 beta,PI51B,PIP5K1-beta,PIP5K1B,PIP5KIbeta,Pipk 5 beta,Pipk 5b,Protein STM 7,Protein STM-7,PtdIns(4)P-5-kinase 1 beta,STM 7,STM7,STM7 LSB,Type I phosphatidylinositol 4 phosphate 5 kinase beta,Type I phosphatidylinositol-4-phosphate 5-kinase beta

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms MSS 4,MSS4,Phosphatidylinositol 4 phosphate 5 kinase type 1 beta,Phosphatidylinositol-4-phosphate 5-kinase type I beta,Phosphatidylinositol-4-phosphate 5-kinase type-1 beta,PI4P5K 1 beta,PI51B,PIP5K1-beta,PIP5K1B,PIP5KIbeta,Pipk 5 beta,Pipk 5b,Protein STM 7,Protein STM-7,PtdIns(4)P-5-kinase 1 beta,STM 7,STM7,STM7 LSB,Type I phosphatidylinositol 4 phosphate 5 kinase beta,Type I phosphatidylinositol-4-phosphate 5-kinase beta
      Swissprot O14986
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PIP5K1B
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endomembrane system. Associated with membranes.
      Tissue specificity Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I å, ∫, and ©, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I å (designated PIPK I ∫ in mouse) is expressed in brain tissue . PIPK I ∫, designated PIPK I a in mouse, is also called STM7. PIPK I © has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PIP5K1B Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PIP5K1B Polyclonal Antibody at dilution 1:30

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