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PLAUR Polyclonal Antibody

Cat:E-AB-14303
Manual MSDS
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Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: WB;IHC
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Product Details
Verified Samples Verified Samples in WB:A549
Verified Samples in IHC:Human lung cancer,Human colon cancer
Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human PLAUR
Abbre PLAUR
Synonyms CD 87;CD87;CD87 antigen;MO 3;MO3;Monocyte activation antigen Mo3;Plasminogen activator receptor urokinase;Plasminogen activator urokinase receptor;PLAUR;U PAR;u plasminogen activator receptor;U-PAR;u-plasminogen activator receptor form 2;UPA receptor;uPAR;UPAR;Urinary plasminogen activator receptor;URKR;Urokinase plasminogen activator receptor;Urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
Swissprot
Calculated MW 37kDa
Cellular Localization Secreted and Cell membrane.
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cardiovascular; Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.