PLEKHA1 Polyclonal Antibody (E-AB-52629)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human ovarian cancer, Human gastric cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PLEKHA1 |
| Abbre | PLEKHA1 |
| Synonyms | family A (phosph, OTTHUMP00000020651, PH domain containing family A member 1, PH domain-containing family A member 1, PKHA1, Pleckstrin homology domain containing, Pleckstrin homology domain containing A1, Pleckstrin homology domain containing family A member 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cell membrane, Nucleus, Locates to the plasma membrane after treatments that stimulate the production of PtdIns3, 4P2. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. |
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