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PRMT7 Polyclonal Antibody

Cat:E-AB-10554
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: WB
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Product Details
Verified Samples Verified Samples in WB:Human liver
Dilution

WB 1:500-1:2000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human PRMT7
Abbre PRMT7
Synonyms [Myelin basic protein]-arginine N-methyltransferase PRMT7;ANM7;FLJ10640;Histone-arginine N-methyltransferase PRMT7;KIAA1933;Myelin basic protein arginine N methyltransferase;OTTHUMP00000174863;PRMT7;Protein arginine methyltransferase 7;Protein arginine N-methyltransferase 7
Swissprot
Calculated MW 78kDa
Cellular Localization Cytoplasm, cytosol. Nucleus.
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).