PRMT7 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Human liver |
Dilution |
WB 1:500-1:2000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PRMT7 |
Abbre | PRMT7 |
Synonyms | [Myelin basic protein]-arginine N-methyltransferase PRMT7;ANM7;FLJ10640;Histone-arginine N-methyltransferase PRMT7;KIAA1933;Myelin basic protein arginine N methyltransferase;OTTHUMP00000174863;PRMT7;Protein arginine methyltransferase 7;Protein arginine N-methyltransferase 7 |
Swissprot | |
Calculated MW | 78kDa |
Cellular Localization | Cytoplasm, cytosol. Nucleus. |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol