PSD4 Polyclonal Antibody (E-AB-18879)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PSD4 |
| Abbre | PSD4 |
| Synonyms | EFA6B, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B, FLJ36237, FLJ37279, PH and SEC7 domain-containing protein 4, PSD4, Pleckstrin homology and SEC7 domain-containing protein 4, Ppleckstrin and Sec7 domain containing 4 , SEC7 homo |
| Swissprot | |
| Cellular Localization | Cell membrane. Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. |
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