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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer
Verified Samples in IF: HeLa
Dilution IHC 1:100-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human PTGS1 (NP_001258094.1).
Abbre PTGS1
Synonyms COX1,  COX3,  PCOX1,  PES-1,  PGG/HS,  PGHS-1,  PGHS1,  PHS1,  PTGHS,  PTGS1
Swissprot
Cellular Localization Microsome membrane. Endoplasmic reticulum membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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