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Cat.No.:E-AB-F1139A
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Gene ID | 5788 |
References |
1. Thomas M. 1989. Annu. Rev. Immunol. 7:339.
2. Trowbridge I, et al. 1994. Annu. Rev. Immunol. 12:85. |
Form | Liquid |
Clone No. | UCHL1(See Other Available Formats) |
Host | Mouse |
Isotype | Mouse IgG2a, κ |
Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4] [Product E-AB-F09803A] |
Reactivity | Human |
Application | FCM (See the Application Description) |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Unconjugated |
How to select the appropriate detection channel through the spectrogram?
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
Purified Anti-Human CD45RO Antibody[UCHL1] | 25μg, 100μg | Check More |
FITC Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
APC Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PerCP Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine5 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine7 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine5.5 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
PerCP/Cyanine5.5 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
Elab Fluor® 488 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |
Elab Fluor® 647 Anti-Human CD45RO Antibody[UCHL1] | 20Tests, 100Tests, 100Tests×2 | Check More |