Alternate Names	Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119
Swissprot	P15261
References	1. Basu M, et al. 1988. P. Natl. Acad. Sci. USA 85:6282. 2. Codias EK, et al. 1990. J. Immunol. 144:2197.

Product Details

Form	Liquid
Clone No.	GR-20(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833A]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Unconjugated

How to select the appropriate detection channel through the spectrogram?

Background

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD119 Antibody[GR-20]	50μg, 500μg, 1mg	Check More
Biotin Anti-Mouse CD119 Antibody[GR-20]	25μg, 100μg	Check More
PE Anti-Mouse CD119 Antibody[GR-20]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD119 Antibody[GR-20]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD119 Antibody[GR-20]	25μg, 100μg	Check More
APC Anti-Mouse CD119 Antibody[GR-20]	25μg, 100μg	Check More

Citations

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